1-Acetyl-4-(4-fluorobenzoyl)piperidine

Base Information Edit

Chemical Name:1-Acetyl-4-(4-fluorobenzoyl)piperidine
CAS No.:25519-77-1
Molecular Formula:C14H15F2NO2
Molecular Weight:249.285
Hs Code.:2933399090
European Community (EC) Number:247-069-5
UNII:S68W7S9ZPY
DSSTox Substance ID:DTXSID80180218
Nikkaji Number:J250.489H
Wikidata:Q83050754
Mol file:25519-77-1.mol

Synonyms:1-Acetyl-4-(4-fluorobenzoyl)piperidine;1-[4-(4-fluorobenzoyl)piperidin-1-yl]ethanone;S68W7S9ZPY;1-[4-(2,4-difluoro-benzoyl)-piperidin-1-yl]-ethanone;1-acetyl-4-(p-fluorobenzoyl)piperidine;1-(4-(4-Fluorobenzoyl)piperidin-1-yl)ethanone;EINECS 247-069-5;UNII-S68W7S9ZPY;SCHEMBL6212608;DTXSID80180218;1-acetyl-4(4-fluorobenzoyl)piperidine;4-(p-fluorobenzoyl)-1-acetylpiperidine;1-acetyl-4-(p-fluorobenzoyl)-piperidine;1-acetyl-4-(4-fluoro-benzoyl)piperidine;1-(4-(4-FLUOROBENZOYL)-1-PIPERIDINYL)ETHANONE;1-(4-(4-FLUOROBENZOYL)PIPERIDIN-1-YL)ETHAN-1-ONE;ETHANONE, 1-(4-(4-FLUOROBENZOYL)-1-PIPERIDINYL)-

Suppliers and Price of 1-Acetyl-4-(4-fluorobenzoyl)piperidine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AHH
4-(2',4'-Difluorobenzoyl)-1-acetylpiperidine 98%
25g
$ 446.00

Total 11 raw suppliers

Chemical Property of 1-Acetyl-4-(4-fluorobenzoyl)piperidine Edit

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Refractive Index:1.523
Boiling Point:408.064 °C at 760 mmHg
Flash Point:200.59 °C
PSA：37.38000
Density:1.248 g/cm³
LogP:2.34390
XLogP3:1.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:249.11650692
Heavy Atom Count:18
Complexity:316

Purity/Quality:

98%min ^*data from raw suppliers

4-(2',4'-Difluorobenzoyl)-1-acetylpiperidine 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)N1CCC(CC1)C(=O)C2=CC=C(C=C2)F
Uses 1-[4-(2,4-Difluorobenzoyl)piperidin-1-yl]ethanone is a chemical reagent used in the synthesis of antiproliferative agents as well as for piperidines displaying 5-HT2 antagonist activity.

Technology Process of 1-Acetyl-4-(4-fluorobenzoyl)piperidine

There total 10 articles about 1-Acetyl-4-(4-fluorobenzoyl)piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 59084-16-1
1-acetylpiperidine-4-carbonyl chloride

: 1-Acetyl-4-(p-fluorophenyl)piperidine

: 25519-77-1
1-(4-(4-fluorobenzoyl)piperidin-1-yl)ethanone

Guidance literature:: aluminium trichloride; In fluorobenzene;

Reference yield: 60.0%

: 462-06-6
fluorobenzene

: 25503-90-6
1-acetyl-piperidine-4-carboxylic acid

: 25519-77-1
1-(4-(4-fluorobenzoyl)piperidin-1-yl)ethanone

Guidance literature:: 1-acetyl-piperidine-4-carboxylic acid; With thionyl chloride; In 1,2-dichloro-ethane; at 20 ℃; for 1h;

fluorobenzene; With aluminum (III) chloride; In 1,2-dichloro-ethane; at 80 ℃; for 3h;