N,N'-BIS(2-HYDROXYBENZYL)ETHYLENEDIAMINE

Base Information

• Chemical Name: N,N'-BIS(2-HYDROXYBENZYL)ETHYLENEDIAMINE
• CAS No.: 18653-98-0
• Molecular Formula: C16H20N2O2
• Molecular Weight: 272.347
• Mol file: 18653-98-0.mol

Synonyms:o-Cresol,a,a'-(ethylenediimino)di- (7CI,8CI);1,2-Bis(2-hydroxybenzylamino)ethane;2,2'-[Ethylenebis(iminomethylene)]diphenol;Bis(2-hydroxybenzyl)ethylenediamine;N,N'-(1,2-Ethylene)bis(salicylaldamine);N,N'-Bis(2-hydroxybenzyl)-1,2-ethanediamine;N,N'-Bis(2-hydroxybenzyl)ethylenediamine;N,N'-Bis(2-hydroxyphenylmethyl)ethylenediamine;N,N'-Bis(o-hydroxybenzyl)ethylenediamine;N,N'-Di(2-hydroxybenzyl)ethylenediamine;NSC 18496;

Chemical Property of N,N'-BIS(2-HYDROXYBENZYL)ETHYLENEDIAMINE

Chemical Property:

• Melting Point: 118-120 °C
• Boiling Point: 462.3 °C at 760 mmHg
• Flash Point: 153.9 °C
• PSA: 64.52000
• Density: 1.181 g/cm³
• LogP: 2.75900
• Storage Temp.: 2-8°C(protect from light)

Purity/Quality:

99%min ^*data from raw suppliers

N,N'-Bis(2-hydroxybenzyl)ethylenediamine, min. 98% H4 SALEN ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N,N'-BIS(2-HYDROXYBENZYL)ETHYLENEDIAMINE

There total 11 articles about N,N'-BIS(2-HYDROXYBENZYL)ETHYLENEDIAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

N,N'-ethylenebis(salicylideneimine) (94-93-9) → N,N'-bis(2-hydroxybenzyl)ethylenediamine (18653-98-0)

Guidance literature:

With sodium tetrahydroborate; In dichloromethane;

DOI:10.1021/om400555u

Reference yield: 94.0%

N,N'-bis(2-hydroxybenzyl)ethylene diimine → N,N'-bis(2-hydroxybenzyl)ethylenediamine (18653-98-0)

Guidance literature:

With zirconium(IV) borohydride; In tetrahydrofuran; at 25 ℃; for 2h;

DOI:10.1080/00397910008087061

Reference yield: 87.0%

1,3-bis(2'-hydroxy-benzyl)-imidazolidine (93731-55-6) → N,N'-bis(2-hydroxybenzyl)ethylenediamine (18653-98-0)

Guidance literature:

1,3-bis(2'-hydroxy-benzyl)-imidazolidine; With hydrogenchloride; In 1,4-dioxane;

With ammonium hydroxide; In methanol;

DOI:10.1081/SCC-120039502

upstream raw materials:

N,N'-ethylenebis(salicylideneimine)

N,N'-ethylenebis(2-hydroxybenzylideneimine)

1,3-bis(2'-hydroxy-benzyl)-imidazolidine

2-methyl-benzyl alcohol

Downstream raw materials:

N,N'-diphthalidyl-N,N'-disalicyl-ethylenediamine

2,2'-[2-(4-diethylamino-phenyl)-imidazolidine-1,3-diyldimethyl]-bis-phenol

1,3-bis(2-hydroxybenzyl)-2-(naphthalen-1-yl)imidazolidine

2-(anthracen-9-yl)-1,3-bis(2-hydroxybenzyl)imidazolidine

Refernces

• 1、 Elmas, Gamze,Okumu?, Aytu?,Ko?, L.Yasemin,Soltanzade, Hossien,Kílí?, Zeynel,H?kelek, Tuncer,Dal, Hakan,A?ík, Leyla,üstünda?, Zafer,Dündar, Devrim,Yavuz, Makbule. "Phosphorus-nitrogen compounds. Part 29. Syntheses, crystal structures, spectroscopic and stereogenic properties, electrochemical investigations, antituberculosis, antimicrobial and cytotoxic activities and DNA interactions of ansa-spiro-ansa cyclotetrapho". . p. 662 - 676. Retrieved 2014.
• 2、 Vinod Kumar,Philip Anthony, Savarimuthu. "Coordinating ligand functionalized AgNPs for colorimetric sensing: Effect of subtle structural and conformational change of ligand on the selectivity". . p. 64717 - 64724. Retrieved 2014.
• 3、 Fegade, Umesh,Tayade, Shivaji,Chaitanya, G. Krishna,Attarde, Sanjay,Kuwar, Anil. "Fluorescent and chromogenic receptor bearing amine and hydroxyl functionality for iron (III) detection in aqueous solution". . p. 675 - 681. Retrieved 2014.
• 4、 Meker, Sigalit,Braitbard, Ori,Hall, Matthew D.,Hochman, Jacob,Tshuva, Edit Y.. "Specific Design of Titanium(IV) Phenolato Chelates Yields Stable and Accessible, Effective and Selective Anticancer Agents". . p. 9986 - 9995. Retrieved 2016.
• 5、 Choudhary, Neha,De Guadalupe Jaraquemada-Peláez, María,Orvig, Chris,Patrick, Brian O.,Scheiber, Hayden,Zhang, Jiale. "H4HBEDpa: Octadentate Chelate after A. E. Martell". . p. 12855 - 12869. Retrieved 2021/09/11.
• 6、 Hazari, Alokesh,Diaz, Carmen,Ghosh, Ashutosh. "H-bond assisted coordination bond formation in the 1D chains based on azido and phenoxido bridged tetranuclear Cu(II) complexes with reduced Schiff base ligands". . p. 16 - 24. Retrieved 2018/01/17.