Ethyl 5-cyano-4-methyl-6-oxo-1,6-dihydropyridine-2-carboxylate

Base Information

Chemical Name:Ethyl 5-cyano-4-methyl-6-oxo-1,6-dihydropyridine-2-carboxylate
CAS No.:58610-61-0
Molecular Formula:C10H10 N2 O3
Molecular Weight:206.201
Hs Code.:
NSC Number:122408
DSSTox Substance ID:DTXSID10298310
Wikidata:Q82040044

Synonyms:ethyl 5-cyano-4-methyl-6-oxo-1,6-dihydropyridine-2-carboxylate;58610-61-0;NSC122408;ethyl 5-cyano-4-methyl-6-oxo-1H-pyridine-2-carboxylate;SCHEMBL2587359;DTXSID10298310;SRAULGKDQYDQCY-UHFFFAOYSA-N;NSC-122408;BS-46775;CS-0111317;ethyl5-cyano-4-methyl-6-oxo-1,6-dihydropyridine-2-carboxylate

Suppliers and Price of Ethyl 5-cyano-4-methyl-6-oxo-1,6-dihydropyridine-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 14 raw suppliers

Chemical Property of Ethyl 5-cyano-4-methyl-6-oxo-1,6-dihydropyridine-2-carboxylate

Chemical Property:

Vapor Pressure:3.23E-06mmHg at 25°C
Boiling Point:387.7°Cat760mmHg
Flash Point:188.3°C
PSA：82.95000
Density:1.26g/cm³
LogP:0.73168
XLogP3:0.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:206.06914219
Heavy Atom Count:15
Complexity:423

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CC(=C(C(=O)N1)C#N)C

Technology Process of Ethyl 5-cyano-4-methyl-6-oxo-1,6-dihydropyridine-2-carboxylate

There total 4 articles about Ethyl 5-cyano-4-methyl-6-oxo-1,6-dihydropyridine-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: ethyl (3E)-4-ethoxy-2-oxopent-3-enoate

: 107-91-5
cyanoacetic acid amide

: 58610-61-0
ethyl 5-cyano-4-methyl-6-oxo-1, 6-dihydropyridine-2-carboxylate

Guidance literature:: With potassium carbonate; In acetone; Heating;
DOI:10.1016/0040-4039(96)01204-X

Reference yield: 65.7%

: ethyl 4-ethoxy-2-oxopent-3-enoate

: 107-91-5
cyanoacetic acid amide

: 58610-61-0
ethyl 5-cyano-4-methyl-6-oxo-1, 6-dihydropyridine-2-carboxylate

Guidance literature:: With potassium carbonate; In acetone; for 10h; Reflux;

Reference yield:

: 615-79-2
ethyl 2,4-diketopentanoate

: 58610-61-0
ethyl 5-cyano-4-methyl-6-oxo-1, 6-dihydropyridine-2-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: ammonium chloride / ethanol / 20 °C

2: potassium carbonate / acetone / 10 h / Reflux

With potassium carbonate; ammonium chloride; In ethanol; acetone;