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615-79-2 Usage


Ethyl 2,4-dioxovalerate is an organic compound that serves as an important intermediate in the synthesis of various pharmaceuticals and chemical compounds. It is characterized by its ability to form a 2,4-dioxovalerate group, which can be incorporated into different molecular structures.


Used in Pharmaceutical Industry:
Ethyl 2,4-dioxovalerate is used as a key intermediate in the synthesis of 1H-pyrazolo[3,4-d]pyridazin-7(6H)-one core analogs, which are important for the development of pyrazole-based pharmaceuticals. These analogs have potential applications in the treatment of various diseases and disorders due to their unique chemical properties and biological activities.
Used in Chemical Synthesis:
Ethyl 2,4-dioxovalerate is used as a versatile building block in the synthesis of a wide range of chemical compounds. Its 2,4-dioxovalerate group can be easily incorporated into various molecular structures, making it a valuable component in the development of new materials and products.

Check Digit Verification of cas no

The CAS Registry Mumber 615-79-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,1 and 5 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 615-79:
72 % 10 = 2
So 615-79-2 is a valid CAS Registry Number.

615-79-2 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail
  • TCI America

  • (R0165)  Ethyl 2,4-Dioxovalerate  >98.0%(GC)(T)

  • 615-79-2

  • 5g

  • 690.00CNY

  • Detail
  • TCI America

  • (R0165)  Ethyl 2,4-Dioxovalerate  >98.0%(GC)(T)

  • 615-79-2

  • 25g

  • 2,650.00CNY

  • Detail
  • Alfa Aesar

  • (A13808)  Ethyl acetopyruvate, 98%   

  • 615-79-2

  • 5g

  • 284.0CNY

  • Detail
  • Alfa Aesar

  • (A13808)  Ethyl acetopyruvate, 98%   

  • 615-79-2

  • 25g

  • 1243.0CNY

  • Detail
  • Alfa Aesar

  • (A13808)  Ethyl acetopyruvate, 98%   

  • 615-79-2

  • 100g

  • 3598.0CNY

  • Detail



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017


1.1 GHS Product identifier

Product name Ethyl 2,4-dioxovalerate

1.2 Other means of identification

Product number -
Other names Pentanoic acid, 2,4-dioxo-, ethyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:615-79-2 SDS

615-79-2Relevant articles and documents

Antitubercular 2-Pyrazolylpyrimidinones: Structure-Activity Relationship and Mode-of-Action Studies

Soares De Melo, Candice,Singh, Vinayak,Myrick, Alissa,Simelane, Sandile B.,Taylor, Dale,Brunschwig, Christel,Lawrence, Nina,Schnappinger, Dirk,Engelhart, Curtis A.,Kumar, Anuradha,Parish, Tanya,Su, Qin,Myers, Timothy G.,Boshoff, Helena I. M.,Barry, Clifton E.,Sirgel, Frederick A.,Van Helden, Paul D.,Buchanan, Kirsteen I.,Bayliss, Tracy,Green, Simon R.,Ray, Peter C.,Wyatt, Paul G.,Basarab, Gregory S.,Eyermann, Charles J.,Chibale, Kelly,Ghorpade, Sandeep R.

, p. 719 - 740 (2021/02/03)

Phenotypic screening of a Medicines for Malaria Venture compound library against Mycobacterium tuberculosis (Mtb) identified a cluster of pan-active 2-pyrazolylpyrimidinones. The biology triage of these actives using various tool strains of Mtb suggested a novel mechanism of action. The compounds were bactericidal against replicating Mtb and retained potency against clinical isolates of Mtb. Although selected MmpL3 mutant strains of Mtb showed resistance to these compounds, there was no shift in the minimum inhibitory concentration (MIC) against a mmpL3 hypomorph, suggesting mutations in MmpL3 as a possible resistance mechanism for the compounds but not necessarily as the target. RNA transcriptional profiling and the checkerboard board 2D-MIC assay in the presence of varying concentrations of ferrous salt indicated perturbation of the Fe-homeostasis by the compounds. Structure-activity relationship studies identified potent compounds with good physicochemical properties and in vitro microsomal metabolic stability with moderate selectivity over cytotoxicity against mammalian cell lines.

Synthesis, nematicidal activity and docking study of novel chromone derivatives containing substituted pyrazole

Li, Wei,Li, Jiuhui,Shen, Hongfeng,Cheng, Jiagao,Li, Zhong,Xu, Xiaoyong

supporting information, p. 911 - 914 (2017/11/01)

A series of chromone derivatives containing substituted pyrazole were designed and synthesized. Preliminary bioassays showed that most of the synthesized compounds exhibited good nematicidal activity in vivo against Meloidogyne incognita at 10 mg/L. Among the tested compounds, A10 and A11 exhibited 100% inhibition rates. In addition, the molecular docking results indicated that both compound A10 and A11 interacts with amino acid residue Tyr121, Trp279, Tyr70, Trp84 and Phe330 of AChE via hydrogen bond and π–π stacking. This investigation suggested that the chromone containing substituted pyrazole scaffold could be further optimized to explore novel, high-bioactivity nematicidal leads.

Synthesis and insecticidal activities of novel 1H-pyrazole-5-carboxylic acid derivatives

Huang, Danling,Liu, Aiping,Liu, Weidong,Liu, Xingping,Ren, Yeguo,Zheng, Xi,Pei, Hui,Xiang, Jun,Huang, Mingzhi,Wang, Xiaoguang

, p. 455 - 460 (2017/12/18)

Fourteen 1H-pyrazole-5-carboxylic acid derivatives containing oxazole and thiazole rings were synthesized and characterized by 1H NMR, mass spectrometry and elemental analysis. Most target compounds were obtained in overall yields in the range of 30-50%. The insecticidal activities of these new compounds against Aphis fabae were evaluated. The bioassays' results indicate that some of these compounds exhibit good activities, especially compound 7h which shows 85.7% mortality against A. fabae at a concentration of 12.5 mg/L. This activity is comparable to that of the commercial insecticide imidacloprid.

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