1-(3,4-Dihydro-6-methoxy-2H-1-benzopyran-4-yl)-4-(2-methoxyphenyl)piperazine dihydrochloride

Base Information

Chemical Name:1-(3,4-Dihydro-6-methoxy-2H-1-benzopyran-4-yl)-4-(2-methoxyphenyl)piperazine dihydrochloride
CAS No.:81816-72-0
Molecular Formula:C₂₁H₂₆N₂O₃*2ClH
Molecular Weight:427.371
Hs Code.:
DSSTox Substance ID:DTXSID001002239

Synonyms:1-(3,4-Dihydro-6-methoxy-2H-1-benzopyran-4-yl)-4-(2-methoxyphenyl)piperazine dihydrochloride;81816-72-0;Piperazine, 1-(3,4-dihydro-6-methoxy-2H-1-benzopyran-4-yl)-4-(2-methoxyphenyl)-, dihydrochloride;DTXSID001002239;LS-111656;1-(6-Methoxy-3,4-dihydro-2H-1-benzopyran-4-yl)-4-(2-methoxyphenyl)piperazine--hydrogen chloride (1/2)

Suppliers and Price of 1-(3,4-Dihydro-6-methoxy-2H-1-benzopyran-4-yl)-4-(2-methoxyphenyl)piperazine dihydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1-(3,4-Dihydro-6-methoxy-2H-1-benzopyran-4-yl)-4-(2-methoxyphenyl)piperazine dihydrochloride

Chemical Property:

Vapor Pressure:1.79E-09mmHg at 25°C
Boiling Point:482.7°Cat760mmHg
Flash Point:137.8°C
Density:g/cm³
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:426.1476981
Heavy Atom Count:28
Complexity:441

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC2=C(C=C1)OCCC2N3CCN(CC3)C4=CC=CC=C4OC.Cl.Cl

Technology Process of 1-(3,4-Dihydro-6-methoxy-2H-1-benzopyran-4-yl)-4-(2-methoxyphenyl)piperazine dihydrochloride

There total 5 articles about 1-(3,4-Dihydro-6-methoxy-2H-1-benzopyran-4-yl)-4-(2-methoxyphenyl)piperazine dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5802-17-5
6-methoxychroman-4-one

: 81816-72-0
1-(6-Methoxy-chroman-4-yl)-4-(2-methoxy-phenyl)-piperazine; hydrochloride

Guidance literature:: Multi-step reaction with 5 steps

1: hydroxylamine hydrochloride, potassium carbonate / ethanol

2: hydrogene / Raney nickel / ethanol

3: ethanol

4: thionyl chloride / CHCl₃

5: sodium iodide, sodium carbonate / butan-1-ol

With thionyl chloride; hydroxylamine hydrochloride; hydrogen; sodium carbonate; potassium carbonate; sodium iodide; nickel; In ethanol; chloroform; butan-1-ol;

Reference yield:

: 67858-18-8
6-methoxy-chroman-4-one oxime

: 81816-72-0
1-(6-Methoxy-chroman-4-yl)-4-(2-methoxy-phenyl)-piperazine; hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1: hydrogene / Raney nickel / ethanol

2: ethanol

3: thionyl chloride / CHCl₃

4: sodium iodide, sodium carbonate / butan-1-ol

With thionyl chloride; hydrogen; sodium carbonate; sodium iodide; nickel; In ethanol; chloroform; butan-1-ol;

Reference yield:

: 81816-60-6
6-methoxychroman-4-amine

: 81816-72-0
1-(6-Methoxy-chroman-4-yl)-4-(2-methoxy-phenyl)-piperazine; hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: ethanol

2: thionyl chloride / CHCl₃

3: sodium iodide, sodium carbonate / butan-1-ol

With thionyl chloride; sodium carbonate; sodium iodide; In ethanol; chloroform; butan-1-ol;