3-(1-ethylpyrrolidin-3-yl)-1H-indole

Base Information

Chemical Name:3-(1-ethylpyrrolidin-3-yl)-1H-indole
CAS No.:3671-01-0
Molecular Formula:C14H18N2
Molecular Weight:214.31
Hs Code.:2933990090
DSSTox Substance ID:DTXSID00957944
Nikkaji Number:J41.058F
Mol file:3671-01-0.mol

Synonyms:3-(1-ethylpyrrolidin-3-yl)-1H-indole;3671-01-0;BRN 1573287;3-(1-Ethyl-3-pyrrolidinyl)indole;INDOLE, 3-(1-ETHYL-3-PYRROLIDINYL)-;3-(1-Ethyl-3-pyrrolidinyl)-1H-indole;5-23-07-00375 (Beilstein Handbook Reference);SCHEMBL19210848;DTXSID00957944;LS-83098;1H-Indole, 3-(1-ethyl-3-pyrrolidinyl)-;NL87650000

Suppliers and Price of 3-(1-ethylpyrrolidin-3-yl)-1H-indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 3-(1-ethylpyrrolidin-3-yl)-1H-indole

Chemical Property:

Vapor Pressure:8.56E-06mmHg at 25°C
Boiling Point:374.1°Cat760mmHg
Flash Point:180°C
PSA：19.03000
Density:1.104g/cm³
LogP:2.91500
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:214.146998583
Heavy Atom Count:16
Complexity:241

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN1CCC(C1)C2=CNC3=CC=CC=C32

Technology Process of 3-(1-ethylpyrrolidin-3-yl)-1H-indole

There total 5 articles about 3-(1-ethylpyrrolidin-3-yl)-1H-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3670-95-9
1-ethyl-3-indol-3-yl-pyrrolidine-2,5-dione

: 3671-01-0
3-(1-ethyl-pyrrolidin-3-yl)-indole

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; for 4h; Reflux;
DOI:10.1016/j.bmcl.2011.05.106

Reference yield:

: 128-53-0
N-Ethylmaleimide

: 3671-01-0
3-(1-ethyl-pyrrolidin-3-yl)-indole

Guidance literature:: Multi-step reaction with 2 steps

1.1: magnesium; methyl iodide / tetrahydrofuran / 1 h / 25 - 30 °C / Inert atmosphere

1.2: 3 h / 70 °C / Inert atmosphere

2.1: lithium aluminium tetrahydride / tetrahydrofuran / 4 h / Reflux

With lithium aluminium tetrahydride; magnesium; methyl iodide; In tetrahydrofuran;
DOI:10.1016/j.bmcl.2011.05.106

Reference yield:

: 1006-94-6
5-methoxylindole

: 3671-01-0
3-(1-ethyl-pyrrolidin-3-yl)-indole

Guidance literature:: Multi-step reaction with 3 steps

1.1: 0.5 h / 50 °C

1.2: 0.5 h / 80 °C

2.1: 1 h / 180 °C

3.1: lithium aluminium tetrahydride / 4 h / Reflux

With lithium aluminium tetrahydride;
DOI:10.14233/ajchem.2013.15443