Salicylic acid, 2-isopropylhydrazide

Base Information

• Chemical Name: Salicylic acid, 2-isopropylhydrazide
• CAS No.: 3583-75-3
• Molecular Formula: C₁₀H₁₄N₂O₂
• Molecular Weight: 194.233
• NSC Number: 51997
• UNII: K4DF8QNH1J
• DSSTox Substance ID: DTXSID60189365
• Wikidata: Q83061429
• ChEMBL ID: CHEMBL3277580
• Mol file: 3583-75-3.mol

Synonyms:Salicylic acid, 2-isopropylhydrazide;K4DF8QNH1J;3583-75-3;NSC-51997;N'-(1-Methylethyl)salicylic acid hydrazide;NSC 51997;BRN 2370016;N(sup 2)-Isopropylsalicyclic acid hydrazide;NSC51997;UNII-K4DF8QNH1J;CHEMBL3277580;DTXSID60189365;BENZOIC ACID, 2-HYDROXY-, 2-(1-METHYLETHYL)HYDRAZIDE

Chemical Property of Salicylic acid, 2-isopropylhydrazide

Chemical Property:

• Boiling Point: 295.2°Cat760mmHg
• Flash Point: 132.3°C
• Density: 1.139g/cm³
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 194.105527694
• Heavy Atom Count: 14
• Complexity: 195

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)NNC(=O)C1=CC=CC=C1O

Technology Process of Salicylic acid, 2-isopropylhydrazide

There total 2 articles about Salicylic acid, 2-isopropylhydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-hydroxy-N'-(propan-2-ylidene)benzohydrazide (54009-57-3) → Salicylsaeure- (3583-75-3)

Guidance literature:

With hydrogen; platinum(IV) oxide; In ethanol;

DOI:10.1021/jm50018a004

Reference yield:

→ Salicylsaeure- (3583-75-3)

Guidance literature:

o-OHC6H4-CONHN=C(CH3)2, PtO2, EtOH;

Reference yield:

trans-Crotonaldehyde (123-73-9,4170-30-3) + Salicylsaeure- (3583-75-3) → 1-salicyl-2-isopropyl-3-methyl-5-hydroxypyrazolidine (103607-50-7)

Guidance literature:

In diethyl ether; for 0.166667h; Yield given; Ambient temperature;

DOI:10.1007/BF00515031

upstream raw materials:

2-hydroxy-N'-(propan-2-ylidene)benzohydrazide

Downstream raw materials:

1-salicyl-2-isopropyl-3-methyl-5-hydroxypyrazolidine

1-salicyl-2-isopropyl-5-hydroxypyrazolidine