(R)-2-PROPYLOCTANOIC ACID

Base Information

Chemical Name:(R)-2-PROPYLOCTANOIC ACID
CAS No.:185517-21-9
Molecular Formula:C11H22O2
Molecular Weight:186.294
Hs Code.:
Mol file:185517-21-9.mol

Synonyms:Acide arundique [INN-French];Acidum arundicum [INN-Latin];Arundic acid [INN];Acido ar?ndico [INN-Spanish];(2R)-2-Propyloctanoic acid;

Suppliers and Price of (R)-2-PROPYLOCTANOIC ACID

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
R-(-)-ArundicAcid
5mg
$ 75.00

Tocris
ONO2506
10
$ 207.00

Tocris
ONO2506
50
$ 844.00

Matrix Scientific
(R)-2-Propyloctanoic acid 95+%
250mg
$ 742.00

Matrix Scientific
(R)-2-Propyloctanoic acid 95+%
1g
$ 1647.00

Crysdot
(R)-2-Propyloctanoicacid 95+%
1g
$ 1195.00

Crysdot
(R)-2-Propyloctanoicacid 95+%
250mg
$ 478.00

Cayman Chemical
Arundic Acid
10mg
$ 117.00

Cayman Chemical
Arundic Acid
5mg
$ 72.00

Cayman Chemical
Arundic Acid
25mg
$ 260.00

Total 52 raw suppliers

Chemical Property of (R)-2-PROPYLOCTANOIC ACID

Chemical Property:

Vapor Pressure:0.000557mmHg at 25°C
Refractive Index:1.444
Boiling Point:289.3 °C at 760mmHg
PKA:4.82±0.40(Predicted)
Flash Point:154.2 °C
PSA：37.30000
Density:0.908 g/cm³
LogP:3.45770
Storage Temp.:Refrigerator
Solubility.:Chloroform (Slightly), Ethanol (Slightly), Ethyl Acetate (Slightly)

Purity/Quality:

99%, ^*data from raw suppliers

R-(-)-ArundicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Description Arundic acid is an inhibitor of astrocyte activation. It reduces increases in brain glial fibrillary acid protein (GFAP) and S100β levels, markers of astrocyte activation, in a rat model of permanent focal ischemia induced by middle cerebral artery occlusion when administered at a dose of 10 mg/kg. Arundic acid (3 and 10 mg/kg) decreases the number of TUNEL-positive neurons, reduces infarct size, and improves motor performance in the rotarod test in the same model. It also reduces descent time and time to turn in a pole test, indicating reversal of motor deficits, in a mouse model of MPTP-induced Parkinson''s disease when administered at a dose of 30 mg/kg.
Uses An astrocyte modulating agent, in acute ischemic stroke.

Technology Process of (R)-2-PROPYLOCTANOIC ACID

There total 42 articles about (R)-2-PROPYLOCTANOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 213914-70-6
(2S)-2-(2-propenyl)octanoic acid

: 185517-21-9
(R)-(-)-arundic acid

Guidance literature:: With hydrogen; platinum on activated charcoal; In isopropyl alcohol; for 1.5h; under 7600 Torr;
DOI:10.1246/bcsj.73.423

Reference yield: 98.0%

: 1333204-12-8
(R)-2-propyloctan-1-ol

: 185517-21-9
(R)-(-)-arundic acid

Guidance literature:: (R)-2-propyloctan-1-ol; With sodium hypochlorite; sodium chlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; In water; acetonitrile; at 35 ℃; for 7h; pH=6.7; Inert atmosphere; aq. phosphate buffer;

With sodium hydrogencarbonate; sodium sulfite; In water; acetonitrile; at 0 ℃; pH=8; Inert atmosphere;

With hydrogenchloride; In water; pH=2; Inert atmosphere;
DOI:10.1002/anie.201102562