213914-70-6

Basic information

• Product Name: (2S)-2-(2-propenyl)octanoic acid
• Synonyms: (2S)-2-(2-propenyl)octanoic acid
• CAS NO: 213914-70-6
• Molecular Weight: 184.279
• Mol File: 213914-70-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2S)-2-(2-propenyl)octanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (2S)-2-(2-propenyl)octanoic acid(213914-70-6)
• EPA Substance Registry System: (2S)-2-(2-propenyl)octanoic acid(213914-70-6)

Safety Data

• Hazardous Substances Data: 213914-70-6(Hazardous Substances Data)

Upstream product

• 213914-68-2 N-[(2S)-2-hexyl-4-pentenoyl]-(1S)-(-)-10,2-camphorsultam 

Downstream Products

• 185517-21-9 (R)-(-)-arundic acid 
• 287731-56-0 (2S)-2-hexyl-4-pentenoic acid cyclohexylamine 

Relevant articles and documents

A practical synthesis of optically active (R)-2-propyloctanoic acid: Therapeutic agent for Alzheimer's disease

(R)-2-Propyloctanoic acid has been developed as a novel therapeutic agent for Alzheimer's disease. A large-scale synthesis of this candidate was achieved by using Oppolzer's camphorsultam as a chiral auxiliary under improved conditions. It was essential for the successful synthesis of this compound to utilize a new removal method for the chiral source with a combination of tetrabutylammonium hydroxide and hydrogen peroxide. The present process afforded the desired product in high yield with high optical purity.