2-Phenyl-2-pyrrolidin-1-ylacetamide

Base Information

• Chemical Name: 2-Phenyl-2-pyrrolidin-1-ylacetamide
• CAS No.: 31788-79-1
• Molecular Formula: C12H16 N2 O
• Molecular Weight: 204.272
• Hs Code.: 2933990090
• European Community (EC) Number: 250-803-7
• NSC Number: 163396
• DSSTox Substance ID: DTXSID601304954
• ChEMBL ID: CHEMBL4538299
• Mol file: 31788-79-1.mol

Synonyms:2-Phenyl-2-pyrrolidin-1-ylacetamide;31788-79-1;2-phenyl-2-(pyrrolidin-1-yl)acetamide;NSC163396;EINECS 250-803-7;NSC 163396;ALPHA-PHENYL-1-PYRROLIDINEACETAMIDE;CHEMBL4538299;SCHEMBL12486937;DTXSID601304954;2-Phenyl-2-(1-pyrrolidinyl)acetamide;2-phenyl-2-pyrrolidin-1-yl-acetamide;AKOS022259870;NSC-163396;Z224202980

Chemical Property of 2-Phenyl-2-pyrrolidin-1-ylacetamide

Chemical Property:

• Vapor Pressure: 6E-05mmHg at 25°C
• Boiling Point: 345.8°C at 760 mmHg
• Flash Point: 163°C
• PSA: 46.33000
• Density: 1.159g/cm³
• LogP: 1.94700
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 204.126263138
• Heavy Atom Count: 15
• Complexity: 218

Purity/Quality:

99% ^*data from raw suppliers

2-phenyl-2-(pyrrolidin-1-yl)acetamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCN(C1)C(C2=CC=CC=C2)C(=O)N

Technology Process of 2-Phenyl-2-pyrrolidin-1-ylacetamide

There total 2 articles about 2-Phenyl-2-pyrrolidin-1-ylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-phenyl-2-(pyrrolidin-1-yl)acetonitrile (31466-31-6) → 2-Phenyl-2-pyrrolidinoacetamid (31788-79-1)

Guidance literature:

With sulfuric acid;

Reference yield:

benzaldehyde (100-52-7) → 2-Phenyl-2-pyrrolidinoacetamid (31788-79-1)

Guidance literature:

Multi-step reaction with 2 steps

1: water

2: concentrated sulfuric acid

With sulfuric acid; water;

Reference yield: 84.0%

2-Phenyl-2-pyrrolidinoacetamid (31788-79-1) → 2-Oxo-3-phenyl-2,3,5,6,7,7a-hexahydro-1H-pyrrolo<1,2-a>imidazol

Guidance literature:

With Hg(II)-EDTA; In ethanol; at 80 ℃; for 0.5h;

upstream raw materials:

2-phenyl-2-(pyrrolidin-1-yl)acetonitrile

benzaldehyde