6-Dehydrofluorocortisol acetate

Base Information

Chemical Name:6-Dehydrofluorocortisol acetate
CAS No.:564-57-8
Molecular Formula:C23H29 F O6
Molecular Weight:420.47
Hs Code.:
DSSTox Substance ID:DTXSID00971842
Mol file:564-57-8.mol

Synonyms:6-dehydro-9 alpha-fluorocortisol acetate;6-dehydro-FCAC;6-dehydrofluorocortisol acetate

Suppliers and Price of 6-Dehydrofluorocortisol acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 6-Dehydrofluorocortisol acetate

Chemical Property:

Vapor Pressure:2.18E-16mmHg at 25°C
Boiling Point:590.2°Cat760mmHg
Flash Point:310.7°C
PSA：100.90000
Density:1.32g/cm³
LogP:2.22050
XLogP3:1.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:4
Exact Mass:420.19481680
Heavy Atom Count:30
Complexity:879

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)OCC(=O)C1(CCC2C1(CC(C3(C2C=CC4=CC(=O)CCC43C)F)O)C)O
Isomeric SMILES:CC(=O)OCC(=O)[C@]1(CC[C@@H]2[C@@]1(C[C@@H](C3([C@H]2C=CC4=CC(=O)CC[C@@]43C)F)O)C)O

Technology Process of 6-Dehydrofluorocortisol acetate

There total 5 articles about 6-Dehydrofluorocortisol acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1812-91-5
21-acetoxy-9-fluoro-11β,17-dihydroxy-5α-pregnane-3,20-dione

: 564-57-8
21-Acetoxy-9α-fluor-11β.17α-dihydroxy-pregna-4,6-dien-3.20-dion

Guidance literature:: With bromine; Erhitzen des Reaktionsprodukts mit 2,4,6-Trimethyl-pyridin;
DOI:10.1021/ja01620a076 DOI:10.1021/ja01616a094

Reference yield:

: 514-36-3
fludrocortisone acetate

: 564-57-8
21-Acetoxy-9α-fluor-11β.17α-dihydroxy-pregna-4,6-dien-3.20-dion

Guidance literature:: Multi-step reaction with 2 steps

1: palladium / Hydrogenation

2: bromine / Erhitzen des Reaktionsprodukts mit 2,4,6-Trimethyl-pyridin

With bromine; palladium;
DOI:10.1021/ja01620a076 DOI:10.1021/ja01616a094