9H-Pyrido(3,4-b)indole, 1-methyl-8-nitro-

Base Information

Chemical Name:9H-Pyrido(3,4-b)indole, 1-methyl-8-nitro-
CAS No.:102207-02-3
Molecular Formula:C12H9 N3 O2
Molecular Weight:227.222
Hs Code.:
ChEMBL ID:CHEMBL5191335
DSSTox Substance ID:DTXSID70144768
Nikkaji Number:J85.805F

Synonyms:8-Nitroharman;9H-Pyrido(3,4-b)indole, 1-methyl-8-nitro-;102207-02-3;1-Methyl-8-nitro-9h-pyrido[3,4-b]indole;BRN 0223508;5-23-08-00263 (Beilstein Handbook Reference);CHEMBL5191335;SCHEMBL16421952;DTXSID70144768

Suppliers and Price of 9H-Pyrido(3,4-b)indole, 1-methyl-8-nitro-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 9H-Pyrido(3,4-b)indole, 1-methyl-8-nitro-

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:227.069476538
Heavy Atom Count:17
Complexity:317

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC=CC2=C1NC3=C2C=CC=C3[N+](=O)[O-]

Technology Process of 9H-Pyrido(3,4-b)indole, 1-methyl-8-nitro-

There total 6 articles about 9H-Pyrido(3,4-b)indole, 1-methyl-8-nitro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 486-84-0
harmane

: 102207-02-3
8-nitro-1-methyl-9H-pyrido[3,4-b]indole

: 38314-91-9
6-nitro-1-methyl-9H-pyrido[3,4-b]indole

Guidance literature:: With sodium nitrate; trifluoroacetic acid; at 0 - 20 ℃; for 6h;
DOI:10.1021/jf404840x

Reference yield:

: 2506-10-7
eleagnine

: 102207-02-3
8-nitro-1-methyl-9H-pyrido[3,4-b]indole

: 38314-91-9
6-nitro-1-methyl-9H-pyrido[3,4-b]indole

Guidance literature:: Multi-step reaction with 2 steps

1: maleic acid; palladium on activated charcoal / water / 8 h / Reflux

2: sodium nitrate; trifluoroacetic acid / 6 h / 0 - 20 °C

With sodium nitrate; palladium on activated charcoal; maleic acid; trifluoroacetic acid; In water;
DOI:10.1021/jf404840x

Reference yield:

: 61-54-1
tryptamine

: 102207-02-3
8-nitro-1-methyl-9H-pyrido[3,4-b]indole

: 38314-91-9
6-nitro-1-methyl-9H-pyrido[3,4-b]indole

Guidance literature:: Multi-step reaction with 3 steps

1.1: sulfuric acid / water / 0.5 h / 20 °C

1.2: 7 h / Reflux

2.1: maleic acid; palladium on activated charcoal / water / 8 h / Reflux

3.1: sodium nitrate; trifluoroacetic acid / 6 h / 0 - 20 °C

With sodium nitrate; sulfuric acid; palladium on activated charcoal; maleic acid; trifluoroacetic acid; In water; 1.1: |Pictet-Spengler Synthesis / 1.2: |Pictet-Spengler Synthesis;
DOI:10.1021/jf404840x