(+)-(1R,2S)-1,2-Epoxy-1,2,3,4-tetrahydrodibenz(c,h)acridine

Base Information

Chemical Name:(+)-(1R,2S)-1,2-Epoxy-1,2,3,4-tetrahydrodibenz(c,h)acridine
CAS No.:93781-05-6
Molecular Formula:C21H15NO
Molecular Weight:297.3499
Hs Code.:
UNII:X3RQ97U8FE
DSSTox Substance ID:DTXSID60917983
Wikidata:Q82889819

Synonyms:X3RQ97U8FE;93781-05-6;(+)-(1R,2S)-1,2-Epoxy-1,2,3,4-tetrahydrodibenz(c,h)acridine;(1aS)-1a,2,3,13c-Tetrahydrobenz(c)oxireno(5,6)benz(1,2-h)acridine;Benz(c)oxireno(5,6)benz(1,2-h)acridine, 1a,2,3,13c-tetrahydro-, (1aS)-;CCRIS 8825;UNII-X3RQ97U8FE;CCRIS-8825;DTXSID60917983;1a,2,3,13c-Tetrahydrobenzo[c][1]benzoxireno[2,3-h]acridine;(1AS,13CR)-1A,2,3,13C-TETRAHYDROBENZ[C]OXIRENO[5,6]BENZ[1,2-H]ACRIDINE;(1AS,13CR)-1A,2,3,13C-TETRAHYDROBENZO(C)(1)BENZOXIRENO(2,3-H)ACRIDINE;BENZ(C)OXIRENO(5,6)BENZ(1,2-H)ACRIDINE, 1A,2,3,13C-TETRAHYDRO-, (1AS,13CR)-;BENZO(C)-1-BENZOXIRENO(2,3-H)ACRIDINE, 1A,2,3,13C-TETRAHYDRO-, (1AS,13CR)-

Suppliers and Price of (+)-(1R,2S)-1,2-Epoxy-1,2,3,4-tetrahydrodibenz(c,h)acridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (+)-(1R,2S)-1,2-Epoxy-1,2,3,4-tetrahydrodibenz(c,h)acridine

Chemical Property:

Vapor Pressure:7.72E-12mmHg at 25°C
Boiling Point:556.2°Cat760mmHg
Flash Point:194.8°C
Density:1.341g/cm³
XLogP3:4.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:297.115364102
Heavy Atom Count:23
Complexity:479

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2=C(C3C1O3)C4=C(C=C2)C=C5C=CC6=CC=CC=C6C5=N4
Isomeric SMILES:C1CC2=C([C@@H]3[C@H]1O3)C4=C(C=C2)C=C5C=CC6=CC=CC=C6C5=N4

Technology Process of (+)-(1R,2S)-1,2-Epoxy-1,2,3,4-tetrahydrodibenz(c,h)acridine

There total 13 articles about (+)-(1R,2S)-1,2-Epoxy-1,2,3,4-tetrahydrodibenz(c,h)acridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 93716-15-5,93781-03-4
trans-2-bromo-1-hydroxy-1,2,3,4-tetrahydrodibenzacridine

: 76186-88-4,93716-17-7,93781-04-5,93781-05-6
(+/-)-1,2-epoxy-1,2,3,4-tetrahydrodibenzacridine

Guidance literature:: With Amberlite-400; In tetrahydrofuran; for 1h; Ambient temperature;
DOI:10.1021/jo00201a019

Reference yield: 11.0%

: 93716-18-8,93781-01-2
(S)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid (1R,2R)-2-bromo-1,2,3,4-tetrahydro-dibenzo[c,h]acridin-1-yl ester

: 224-53-3
dibenz[c,h]acridine

: 93781-05-6
(+)-(1R,2S)-1,2-epoxy-1,2,3,4-tetrahydrodibenzacridine

Guidance literature:: With sodium methylate; In tetrahydrofuran; at 0 - 5 ℃; for 312h;
DOI:10.1021/jo00201a019

Reference yield:

: 90-15-3
α-naphthol

: 76186-88-4,93716-17-7,93781-04-5,93781-05-6
(+/-)-1,2-epoxy-1,2,3,4-tetrahydrodibenzacridine

Guidance literature:: Multi-step reaction with 5 steps

1: 12.9 percent / 0.25 h / 250 °C

2: 26 percent / HOAc, aq. ceric ammonium sulfate / benzene / 96 h / 40 - 45 °C

3: 90 percent / conc. HCl, HOAc / 2.5 h / 65 °C

4: 79 percent / N-bromoacetamid (NBA), aq. HCl / tetrahydrofuran / 1 h / 0 - 5 °C

5: 67 percent / Amberlite-400 / tetrahydrofuran / 1 h / Ambient temperature

With hydrogenchloride; cerium(IV) ammonium sulphate; Amberlite-400; acetic acid; N-bromoacetamide; In tetrahydrofuran; benzene;
DOI:10.1021/jo00201a019