2-(piperidin-1-ylcarbonyl)-3,4-dihydro-2H-1,4-benzoxazine hydrochloride

Base Information

• Chemical Name: 2-(piperidin-1-ylcarbonyl)-3,4-dihydro-2H-1,4-benzoxazine hydrochloride
• CAS No.: 92292-97-2
• Molecular Formula: C₁₄H₁₈N₂O₂
• Molecular Weight: 246.309
• Hs Code.: 2934999090
• DSSTox Substance ID: DTXSID60585828
• Mol file: 92292-97-2.mol

Synonyms:2-(piperidin-1-ylcarbonyl)-3,4-dihydro-2H-1,4-benzoxazine hydrochloride;1052543-19-7;3,4-dihydro-2H-1,4-benzoxazin-2-yl(piperidin-1-yl)methanone;hydrochloride;2-(PIPERIDINE-1-CARBONYL)-3,4-DIHYDRO-2H-1,4-BENZOXAZINE HYDROCHLORIDE;DTXSID60585828;EN300-14545;(3,4-Dihydro-2H-1,4-benzoxazin-2-yl)(piperidin-1-yl)methanone--hydrogen chloride (1/1);2-(PIPERIDINE-1-CARBONYL)-3,4-DIHYDRO-2H-1,4-BENZOXAZINEHYDROCHLORIDE

Chemical Property of 2-(piperidin-1-ylcarbonyl)-3,4-dihydro-2H-1,4-benzoxazine hydrochloride

Chemical Property:

• Vapor Pressure: 1.89E-08mmHg at 25°C
• Melting Point: 118-120 °C
• Boiling Point: 454.5°Cat760mmHg
• PKA: 3?+-.0.40(Predicted)
• Flash Point: 228.7°C
• PSA: 41.57000
• Density: 1.183g/cm³
• LogP: 2.74990
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 282.1135055
• Heavy Atom Count: 19
• Complexity: 302

Purity/Quality:

2-(PIPERIDIN-1-YLCARBONYL)-3,4-DIHYDRO-2H-1,4-BENZOXAZINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCN(CC1)C(=O)C2CNC3=CC=CC=C3O2.Cl

Technology Process of 2-(piperidin-1-ylcarbonyl)-3,4-dihydro-2H-1,4-benzoxazine hydrochloride

There total 2 articles about 2-(piperidin-1-ylcarbonyl)-3,4-dihydro-2H-1,4-benzoxazine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-amino-phenol (95-55-6) → Benzomorpholin-carbonsaeure-(2)-piperidid (92292-97-2)

Guidance literature:

Multi-step reaction with 2 steps

1: K₂CO₃ / acetone / Heating

2: ethanol / Ambient temperature

With potassium carbonate; In ethanol; acetone;

Reference yield:

piperidine (110-89-4) + 3,4-Dihydro-2H-1,4-benzoxazin-2-carbnsaeuremethylester (82756-71-6) → Benzomorpholin-carbonsaeure-(2)-piperidid (92292-97-2)

Guidance literature:

In ethanol; Ambient temperature;

upstream raw materials:

piperidine

3,4-Dihydro-2H-1,4-benzoxazin-2-carbnsaeuremethylester

2-amino-phenol