2,3-Dimethoxy-6-methyl-8,9-(methylenedioxy)-11H-indeno(1,2-c)isoquinoline

Base Information

• Chemical Name: 2,3-Dimethoxy-6-methyl-8,9-(methylenedioxy)-11H-indeno(1,2-c)isoquinoline
• CAS No.: 87922-29-0
• Molecular Formula: C20H18 N O4 . Cl
• Molecular Weight: 371.82
• NSC Number: 339330
• UNII: PPC342YN8S
• DSSTox Substance ID: DTXSID201007873
• ChEMBL ID: CHEMBL8624
• Mol file: 87922-29-0.mol

Synonyms:2,3-dimethoxy-6-methyl-8,9-(methylenedioxy)-11H-indeno(1,2-c)isoquinoline;2,3-dimethoxy-6-methyl-8,9-(methylenedioxy)-11H-indeno(1,2-c)isoquinolinium chloride;2,3-DMMII

Chemical Property of 2,3-Dimethoxy-6-methyl-8,9-(methylenedioxy)-11H-indeno(1,2-c)isoquinoline

Chemical Property:

• Boiling Point: 642.2oC at 760 mmHg
• Flash Point: 199oC
• PSA: 40.80000
• Density: 1.36g/cm3
• LogP: -0.01460
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 2
• Exact Mass: 371.0924357
• Heavy Atom Count: 26
• Complexity: 502

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C[N+]1=CC2=CC(=C(C=C2C3=C1C4=CC5=C(C=C4C3)OCO5)OC)OC.[Cl-]

Technology Process of 2,3-Dimethoxy-6-methyl-8,9-(methylenedioxy)-11H-indeno(1,2-c)isoquinoline

There total 5 articles about 2,3-Dimethoxy-6-methyl-8,9-(methylenedioxy)-11H-indeno(1,2-c)isoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,4-dimethoxyhomophthalic anhydride (5653-42-9) → 2,3-dimethoxy-6-methyl-8,9-(methylenedioxy)-11H-indeno[1,2-c]isoquinolinium chloride (87922-29-0)

Guidance literature:

Multi-step reaction with 4 steps

1: 75 percent / CHCl₃ / 0.5 h / Ambient temperature

2: 49 percent / polyphosphoric acid / 1 h / 70 - 80 °C

3: 61 percent / lithium aluminum hydride / tetrahydrofuran / 20 h / Heating

4: 1.) 5percent Pd/C, 2.) 15percent aq. NaCl / 1.) glacial acetic acid, reflux, 20 h, 2.) water, ethanol

With palladium on activated charcoal; lithium aluminium tetrahydride; PPA; sodium chloride; In tetrahydrofuran; chloroform;

DOI:10.1021/jm00370a021

Reference yield:

N-[(1E)-1,3-benzodioxol-5-ylmethylene]methanamine (113975-93-2) → 2,3-dimethoxy-6-methyl-8,9-(methylenedioxy)-11H-indeno[1,2-c]isoquinolinium chloride (87922-29-0)

Guidance literature:

Multi-step reaction with 4 steps

1: 75 percent / CHCl₃ / 0.5 h / Ambient temperature

2: 49 percent / polyphosphoric acid / 1 h / 70 - 80 °C

3: 61 percent / lithium aluminum hydride / tetrahydrofuran / 20 h / Heating

4: 1.) 5percent Pd/C, 2.) 15percent aq. NaCl / 1.) glacial acetic acid, reflux, 20 h, 2.) water, ethanol

With palladium on activated charcoal; lithium aluminium tetrahydride; PPA; sodium chloride; In tetrahydrofuran; chloroform;

DOI:10.1021/jm00370a021

Reference yield:

3c-benzo[1,3]dioxol-5-yl-6,7-dimethoxy-2-methyl-1-oxo-1,2,3,4-tetrahydro-isoquinoline-4r-carboxylic acid (64036-07-3) → 2,3-dimethoxy-6-methyl-8,9-(methylenedioxy)-11H-indeno[1,2-c]isoquinolinium chloride (87922-29-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 49 percent / polyphosphoric acid / 1 h / 70 - 80 °C

2: 61 percent / lithium aluminum hydride / tetrahydrofuran / 20 h / Heating

3: 1.) 5percent Pd/C, 2.) 15percent aq. NaCl / 1.) glacial acetic acid, reflux, 20 h, 2.) water, ethanol

With palladium on activated charcoal; lithium aluminium tetrahydride; PPA; sodium chloride; In tetrahydrofuran;

DOI:10.1021/jm00370a021

upstream raw materials:

2,3-dimethoxy-5,6,12α,13α-tetrahydro-11β-hydroxy-6-methyl-8,9-(methylenedioxy)-11H-indeno<1,2-c>isoquinoline

3,4-dimethoxyhomophthalic anhydride

N-[(1E)-1,3-benzodioxol-5-ylmethylene]methanamine

3c-benzo[1,3]dioxol-5-yl-6,7-dimethoxy-2-methyl-1-oxo-1,2,3,4-tetrahydro-isoquinoline-4r-carboxylic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 87922-29-0 2,3-dimethoxy-6-methyl-8,9-(methylenedioxy)-11H-indeno(1,2-c)isoquinoline

Send

Send

Metric Ton KG G Pound L ML

Send

Send