6-Methoxy-1,4-dimethyl-9H-carbazole

Base Information

• Chemical Name: 6-Methoxy-1,4-dimethyl-9H-carbazole
• CAS No.: 18028-57-4
• Molecular Formula: C15H15NO
• Molecular Weight: 225.29
• Hs Code.: 2933990090
• European Community (EC) Number: 241-941-9
• DSSTox Substance ID: DTXSID10170940
• Nikkaji Number: J260.842A
• Wikidata: Q72470855
• ChEMBL ID: CHEMBL477756
• Mol file: 18028-57-4.mol

Synonyms:1,4-dimethyl-6-methoxycarbazole;6-methoxy-1,4-dimethylcarbazole

Chemical Property of 6-Methoxy-1,4-dimethyl-9H-carbazole

Chemical Property:

• Vapor Pressure: 9.02E-07mmHg at 25°C
• Melting Point: 136.5℃
• Boiling Point: 416.8°Cat760mmHg
• Flash Point: 150.6°C
• PSA: 25.02000
• Density: 1.17g/cm³
• LogP: 3.94650
• XLogP3: 4.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 225.115364102
• Heavy Atom Count: 17
• Complexity: 280

Purity/Quality:

97% ^*data from raw suppliers

6-methoxy-1,4-dimethyl-9H-carbazole ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C2C3=C(C=CC(=C3)OC)NC2=C(C=C1)C

Technology Process of 6-Methoxy-1,4-dimethyl-9H-carbazole

There total 8 articles about 6-Methoxy-1,4-dimethyl-9H-carbazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

5-methoxylindole (1006-94-6) + 2,5-hexanedione (110-13-4) → 6-methoxy-1,4-dimethyl-9H-carbazole (18028-57-4)

Guidance literature:

montmorillonite K-10; at 90 ℃; for 0.05h; microwave heating;

DOI:10.1002/adsc.200606200

Reference yield: 95.0%

dimethyl-1,4 methoxy-6 formyl-9 carbazole → 6-methoxy-1,4-dimethyl-9H-carbazole (18028-57-4)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 26h; Product distribution; Heating;

Reference yield: 73.0%

N-(4'-methoxyphenyl)-2,5-dimethyl-N-(toluene-p-sulfonyl)aniline → 6-methoxy-1,4-dimethyl-9H-carbazole (18028-57-4)

Guidance literature:

In ethanol; for 7h; Irradiation;

upstream raw materials:

5-methoxylindole

2,5-hexanedione

4-bromo-m-xylene

N-(4-Methoxy-phenyl)-4-methyl-benzenesulfonamide

Downstream raw materials:

1,4-dimethyl-6-hydroxy-9H-carbazole

1,4-dimethyl-3,8-dinitro-6-methoxy-9H-carbazole

6-methoxy-1,4-dimethyl-9-H-carbazole-3-carbaldehyde

Pentanedioic acid benzyl ester 5,11-dimethyl-6H-pyrido[4,3-b]carbazol-9-yl ester