7-amino-3-(2-bromoethoxy)-4-chloroisocoumarin

Base Information

Chemical Name:7-amino-3-(2-bromoethoxy)-4-chloroisocoumarin
CAS No.:126062-22-4
Molecular Formula:C11H9 Br Cl N O3
Molecular Weight:318.554
Hs Code.:
Mol file:126062-22-4.mol

Synonyms:Abe-cic;Isocoumarin,6a;7-amino-4-chloro-3-(2-bromoethoxy)isocoumarin;1H-2-Benzopyran-1-one,7-amino-3-(2-bromoethoxy)-4-chloro;7-amino-3-(2-bromoethoxy)-4-chloroisocoumarin;

Suppliers and Price of 7-amino-3-(2-bromoethoxy)-4-chloroisocoumarin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 7-amino-3-(2-bromoethoxy)-4-chloroisocoumarin

Chemical Property:

Vapor Pressure:1.62E-10mmHg at 25°C
Boiling Point:509.9°Cat760mmHg
Flash Point:262.2°C
PSA：65.46000
Density:1.73g/cm³
LogP:3.38350

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 7-amino-3-(2-bromoethoxy)-4-chloroisocoumarin

There total 5 articles about 7-amino-3-(2-bromoethoxy)-4-chloroisocoumarin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 141468-73-7
4-chloro-3-(2-bromo-ethoxy)-7-nitro-isocoumarin

: 126062-22-4
7-amino-3-(2-bromoethoxy)-4-chloro-isocoumarin

Guidance literature:: With hydrogen; palladium on activated charcoal; In tetrahydrofuran; at 20 ℃; for 6h; atmospheric pressure;
DOI:10.1016/S0968-0896(03)00235-9

Reference yield:

: 3898-66-6
2-(carboxymethyl)-5-nitrobenzoic acid

: 126062-22-4
7-amino-3-(2-bromoethoxy)-4-chloro-isocoumarin

Guidance literature:: Multi-step reaction with 3 steps

1: 73 percent / H₂SO₄ / 0.12 h / 70 °C

2: 44 percent / PCl₅ / toluene / 15 h / Heating

3: 100 percent / H₂ / Pd/C / tetrahydrofuran / 6 h / 20 °C / atmospheric pressure

With phosphorus pentachloride; sulfuric acid; hydrogen; palladium on activated charcoal; In tetrahydrofuran; toluene;
DOI:10.1016/S0968-0896(03)00235-9

Reference yield:

: 141468-58-8
2-(2-bromo-ethoxycarbonylmethyl)-5-nitro-benzoic acid

: 126062-22-4
7-amino-3-(2-bromoethoxy)-4-chloro-isocoumarin

Guidance literature:: Multi-step reaction with 2 steps

1: 44 percent / PCl₅ / toluene / 15 h / Heating

2: 100 percent / H₂ / Pd/C / tetrahydrofuran / 6 h / 20 °C / atmospheric pressure

With phosphorus pentachloride; hydrogen; palladium on activated charcoal; In tetrahydrofuran; toluene;
DOI:10.1016/S0968-0896(03)00235-9