4-NITROHOMOPHTHALIC ACID

Base Information

• Chemical Name: 4-NITROHOMOPHTHALIC ACID
• CAS No.: 3898-66-6
• Molecular Formula: C9H7NO6
• Molecular Weight: 225.158
• Hs Code.: 2917399090
• Mol file: 3898-66-6.mol

Synonyms:4-NITROHOMOPHTHALIC ACID;2-(CARBOXYMETHYL)-5-NITROBENZOIC ACID

Chemical Property of 4-NITROHOMOPHTHALIC ACID

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 210-215 °C (decomp)
• Boiling Point: 483.982°C at 760 mmHg
• PKA: 2.73±0.22(Predicted)
• Flash Point: 215.052°C
• PSA: 120.42000
• Density: 1.594g/cm³
• LogP: 1.44330
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98%min ^*data from raw suppliers

2-(Carboxymethyl)-5-nitrobenzoicacid 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-NITROHOMOPHTHALIC ACID

There total 11 articles about 4-NITROHOMOPHTHALIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

Homophthalic acid (89-51-0) → 2-(carboxymethyl)-5-nitrobenzoic acid (3898-66-6)

Guidance literature:

With nitric acid; at 0 - 22 ℃;

DOI:10.1021/jm8007085

Reference yield:

6-nitroindan-1-one (24623-24-3) → 4-nitrophthalic acid (610-27-5) + 2-(carboxymethyl)-5-nitrobenzoic acid (3898-66-6)

Guidance literature:

Reference yield:

1-indene (95-13-6) → 2-(carboxymethyl)-5-nitrobenzoic acid (3898-66-6)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium dichromate; sulfuric acid / water / 2 h / 65 °C

2: nitric acid / 2 h / -3 °C

With potassium dichromate; sulfuric acid; nitric acid; In water;

upstream raw materials:

Homophthalic acid

6-nitro-1,2-indanedione

nitric acid

6-nitroindan-1-one

Downstream raw materials:

2-methoxycarbonylmethyl-5-nitro-benzoic acid

4-nitrophthalic acid

2-(2-cyano-ethoxycarbonylmethyl)-5-nitro-benzoic acid

2-[2-(3-bromopropoxy)-2-oxoethyl]-5-nitrobenzoic acid