Etafedrine HCl

Base Information

• Chemical Name: Etafedrine HCl
• CAS No.: 5591-29-7
• Molecular Formula: C12H20ClNO
• Molecular Weight: 229.75
• Hs Code.: 2923900090
• European Community (EC) Number: 227-000-5
• DSSTox Substance ID: DTXSID401342825
• NCI Thesaurus Code: C75032
• ChEMBL ID: CHEMBL2106678
• Mol file: 5591-29-7.mol

Synonyms:etafedrine;etafedrine hydrochloride;etafedrine hydrochloride, (R-(R*,S*))-isomer;etafedrine, (R*,S*)-isomer;etafedrine, R-(R*,S*);etaphedrine;L-N-ethylephedrine

Chemical Property of Etafedrine HCl

Chemical Property:

• Vapor Pressure: 0.000717mmHg at 25°C
• Melting Point: 183-184°
• Boiling Point: 294.8°Cat760mmHg
• Flash Point: 104.5°C
• PSA: 23.47000
• Density: g/cm³
• LogP: 2.86220
• Storage Temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
• Solubility.: Chloroform (Slightly), Methanol (Slightly)
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 229.1233420
• Heavy Atom Count: 15
• Complexity: 154

Purity/Quality:

98%Min ^*data from raw suppliers

EtafedrineHCl(mixtureofdiastereomers) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCN(C)C(C)C(C1=CC=CC=C1)O.Cl
• Uses: Etafedrine is the N-ethylated analogue of Ephedrine (E575000). Etafedrine is a long-acting bronchodilator that acts as a selective β-adrenergic receptor agonist.

Technology Process of Etafedrine HCl

There total 1 articles about Etafedrine HCl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl bromide (74-96-4) + 2-methylamino-1-phenylpropanol (299-42-3,7009-81-6,90-83-5,6912-63-6) → 2-N-ethyl-N-methylamino-1-phenylpropanol hydrochloride (5591-29-7)

Guidance literature:

With hydrogenchloride; Yield given; Multistep reaction; 1.) 25 deg C, 24 h; 100 deg C, 5 h, 2.) ether;

DOI:10.1080/00397919908086248

upstream raw materials:

ethyl bromide

2-methylamino-1-phenylpropanol