Bromoethane

Base Information

• Chemical Name: Bromoethane
• CAS No.: 74-96-4
• Molecular Formula: C2H5Br
• Molecular Weight: 108.966
• Hs Code.: 2903399090
• European Community (EC) Number: 200-825-8
• ICSC Number: 1378
• NSC Number: 8824
• UN Number: 1891
• UNII: LI8384T9PH
• DSSTox Substance ID: DTXSID6020199
• Nikkaji Number: J2.383C
• Wikipedia: Bromoethane
• Wikidata: Q412245
• Metabolomics Workbench ID: 115488
• ChEMBL ID: CHEMBL156378
• Mol file: 74-96-4.mol

Synonyms:bromoethane

Chemical Property of Bromoethane

Chemical Property:

• Appearance/Colour: colourless liquid with an ether-like odour
• Melting Point: -119 °C
• Refractive Index: n20/D 1.425(lit.)
• Boiling Point: 39.2 °C at 760 mmHg
• Flash Point: -23 °C
• PSA: 0.00000
• Density: 1.458 g/cm³
• LogP: 1.40120
• Water Solubility.: 0.91 g/100 mL (20℃)
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 107.95746
• Heavy Atom Count: 3
• Complexity: 2.8
• Transport DOT Label: Poison

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s): F, Xn
• Hazard Codes: F:Flammable;;
• Statements: R11:; R20/22:; R40:
• Safety Statements: S36/37:

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Solvents -> Brominated Solvents
• Canonical SMILES: CCBr
• Inhalation Risk: A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20 °C.
• Effects of Short Term Exposure: The substance is irritating to the eyes. The substance may cause effects on the central nervous system. Exposure could cause unconsciousness.

Technology Process of Bromoethane

There total 337 articles about Bromoethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

orthoformic acid triethyl ester (122-51-0) → ethyl bromide (74-96-4) + ethyl trimethylsilyl ether (1825-62-3) + formic acid ethyl ester (109-94-4)

Guidance literature:

With chloro-trimethyl-silane; sodium bromide; for 2h; Product distribution; Heating; Me₃SiBr generated in situ;

Reference yield:

Acetyl bromide (506-96-7) + benzyl cellosolve (61911-33-9) → ethyl bromide (74-96-4) + 2-ethoxyethyl acetate (111-15-9) + ethylene glycol diacetate (111-55-7,27252-83-1) + benzyl bromide (100-39-0)

Guidance literature:

at 92 ℃;

Reference yield:

Ethyl isovalerate (108-64-5) → ethyl bromide (74-96-4) + 2-bromo-3-methyl-butyryl bromide (26464-05-1)

Guidance literature:

With phosphorus; bromine;

DOI:10.1002/ardp.19532860205

upstream raw materials:

Diazoethan

tetrachloromethane

diethyl sulfate

tetraethoxy orthosilicate

Downstream raw materials:

2-(ethoxymethyl)tetrahydrofuran

1-ethyl-1,2,5,6-tetrahydropyridine

N-Ethylimidazole

2-(4-ethylpiperazin-1-yl)ethan-1-ol

Refernces

• 1、 Lure et al.. "". . . Retrieved 1972.
• 2、 Aditya,Willard. "". . p. 3367,3368. Retrieved 1957.
• 3、 Pevzner. "Synthesis of ethyl 4,5-bis(diethoxyphosphorylmethyl)-3-furoate". . p. 62 - 67. Retrieved 2016.
• 4、 Blanchette, Marcia C.,Holmes, John L.,Lossing, F. P.. "The Ethyl Halides: Stable Neutral and Radical Cation Isomers where X = F, Cl, Br, I". . p. 701 - 709. Retrieved 1987.
• 5、 Yasuhiko, Kondo,Kazumi, Yuki,Takeshi, Yoshida,Niichiro, Tokura. "Nucleophilic Substitution in Binary Mixed Solvents. Kinetics and Transfer Enthalpies of Anions in the Mixed Solvents Methanol+Propylene Carbonate and Methanol+N-methyl-2-pyrrolidone". . p. 812 - 824. Retrieved 1980.
• 6、 Chen, Jing,Zhou, Lei,Liu, Yi-Fan,Hou, Zhao-Wei,Li, Wei,Mbadinga, Serge Maurice,Zhou, Jing,Yang, Tao,Liu, Jin-Feng,Yang, Shi-Zhong,Wu, Xiao-Lin,Gu, Ji-Dong,Mu, Bo-Zhong. "Synthesis and mass spectra of rearrangement bio-signature metabolites of anaerobic alkane degradation via fumarate addition". . . Retrieved 2020/05/01.