Bromoethane

Base Information

• Chemical Name: Bromoethane
• CAS No.: 74-96-4
• Molecular Formula: C2H5Br
• Molecular Weight: 108.966
• Hs Code.: 2903399090
• European Community (EC) Number: 200-825-8
• ICSC Number: 1378
• NSC Number: 8824
• UN Number: 1891
• UNII: LI8384T9PH
• DSSTox Substance ID: DTXSID6020199
• Nikkaji Number: J2.383C
• Wikipedia: Bromoethane
• Wikidata: Q412245
• Metabolomics Workbench ID: 115488
• ChEMBL ID: CHEMBL156378
• Mol file: 74-96-4.mol

Synonyms:bromoethane

Chemical Property of Bromoethane

Chemical Property:

• Appearance/Colour: colourless liquid with an ether-like odour
• Melting Point: -119 °C
• Refractive Index: n20/D 1.425(lit.)
• Boiling Point: 39.2 °C at 760 mmHg
• Flash Point: -23 °C
• PSA: 0.00000
• Density: 1.458 g/cm³
• LogP: 1.40120
• Water Solubility.: 0.91 g/100 mL (20℃)
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 107.95746
• Heavy Atom Count: 3
• Complexity: 2.8
• Transport DOT Label: Poison

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s): F, Xn
• Hazard Codes: F:Flammable;;
• Statements: R11:; R20/22:; R40:
• Safety Statements: S36/37:

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Solvents -> Brominated Solvents
• Canonical SMILES: CCBr
• Inhalation Risk: A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20 °C.
• Effects of Short Term Exposure: The substance is irritating to the eyes. The substance may cause effects on the central nervous system. Exposure could cause unconsciousness.

Technology Process of Bromoethane

There total 337 articles about Bromoethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

orthoformic acid triethyl ester (122-51-0) → ethyl bromide (74-96-4) + ethyl trimethylsilyl ether (1825-62-3) + formic acid ethyl ester (109-94-4)

Guidance literature:

With chloro-trimethyl-silane; sodium bromide; for 2h; Product distribution; Heating; Me₃SiBr generated in situ;

Reference yield:

Acetyl bromide (506-96-7) + benzyl cellosolve (61911-33-9) → ethyl bromide (74-96-4) + 2-ethoxyethyl acetate (111-15-9) + ethylene glycol diacetate (111-55-7,27252-83-1) + benzyl bromide (100-39-0)

Guidance literature:

at 92 ℃;

Reference yield:

Ethyl isovalerate (108-64-5) → ethyl bromide (74-96-4) + 2-bromo-3-methyl-butyryl bromide (26464-05-1)

Guidance literature:

With phosphorus; bromine;

DOI:10.1002/ardp.19532860205

upstream raw materials:

Diazoethan

tetrachloromethane

diethyl sulfate

tetraethoxy orthosilicate

Downstream raw materials:

1-ethyl-piperidine

N-ethylmorpholine;

2-(ethoxymethyl)tetrahydrofuran

2-ethylthiophene

Refernces

The First Synthesis of Bisgermylene and Bisstannylene with Acyclic Structure

10.1246/cl.1994.941

The study reports the first synthesis of bisgermylene and bisstannylene with an acyclic structure. The synthesis was achieved through one-pot, two-step ligand substitution reactions starting from germanium and tin dichlorides. The key chemicals involved include 1,4-dioxane complexes of germanium dichloride (la) and tin dichloride (1b), lithium amide compounds derived from amines such as 1,1,1,3,3,3-hexamethyldisilazane and N,N'-bis(trimethylsilyl)-p-phenylenediamine. These lithium amides played crucial roles in the ligand substitution steps. The products, bisgermylene (5a) and bisstannylene (5b), were isolated by crystallization from diethyl ether and were found to be stable at ambient temperatures under an inert atmosphere. The study also explored the oxidative addition of these compounds to organic halides like ethyl iodide and ethyl bromide, yielding products 6a and 6b, which were characterized by their melting points and NMR spectra. The research aims to extend the understanding of organometallic chemistry involving germanium and tin compounds and their potential applications in polymer synthesis and other organometallic reactions.