Methoxydienone

Base Information

Chemical Name:Methoxydienone
CAS No.:6236-40-4
Molecular Formula:C₂₀H₂₈O₂
Molecular Weight:300.441
Hs Code.:
European Community (EC) Number:219-034-4,228-351-7
UNII:12AU99WIMP
DSSTox Substance ID:DTXSID201036347,DTXSID001045120
Nikkaji Number:J213.193E
Wikipedia:Methoxydienone
Wikidata:Q27251400

Synonyms:Methoxydienone;2322-77-2;13-beta-Ethyl-3-methoxy-gona-2,5(10)-dien-17-one;Methoxygonadiene;Max LMG;13-beta-Ethyl-3-methoxygona-2,5(10)-dien-17-one;Levonorgestrel Impurity R;13-Ethyl-3-methoxy-gona-2,5(10)diene-17-one;UNII-12AU99WIMP;12AU99WIMP;Gona-2,5(10)-dien-17-one, 13-ethyl-3-methoxy-;(8R,9S,13S,14S)-13-ethyl-3-methoxy-4,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-one;13-ethyl-3-methoxygona-2,5(10)-dien-17-one;EINECS 219-034-4;13-Ethyl-3-methoxy-gona-2,5(10)-dien-17-one;6236-40-4;SCHEMBL11506097;DTXSID001045120;DTXSID201036347;BCP10781;CAA32277;MFCD08457893;AKOS015896292;FD12060;AS-13041;LEVONORGESTREL IMPURITY R [EP IMPURITY];Q-102818;13beta-ethyl-3-methoxy-gona-2,5(10)-dien-17-one;Q27251400;(+/-)-13-ethyl-3-methoxygona-2,5(10)-dien-17-one;13-.BETA.-ETHYL-3-METHOXYGONA-2,5(10)-DIEN-17-ONE;(3aS,3bR,9bS,11aS)-11a-ethyl-7-methoxy-1H,2H,3H,3aH,3bH,4H,5H,6H,9H,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-one

Suppliers and Price of Methoxydienone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 15 raw suppliers

Chemical Property of Methoxydienone

Chemical Property:

Vapor Pressure:3.21E-08mmHg at 25°C
Refractive Index:1.551
Boiling Point:448.028 °C at 760 mmHg
Flash Point:188.823 °C
Density:1.097 g/cm³
XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:300.208930132
Heavy Atom Count:22
Complexity:556

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC12CCC3C(C1CCC2=O)CCC4=C3CC=C(C4)OC
Isomeric SMILES:CC[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)CCC4=C3CC=C(C4)OC

Technology Process of Methoxydienone

There total 11 articles about Methoxydienone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 1038-28-4,5772-35-0,14507-49-4,77209-48-4,85798-56-7
dl-3-methoxy-13β-ethylgona-2,5(10)-dien-17β-ol

: 2322-77-2,6236-40-4,17092-08-9,19640-64-3
dl-3-methoxy-13β-ethylgona-2,5(10)-dien-17-one

Guidance literature:: With molecular sieve; aluminum isopropoxide; butanone; In benzene;
DOI:10.1002/hlca.19850680430

Reference yield:

: 2-Ethyl-3-vinyl-cyclopentanone

: 2322-77-2,6236-40-4,17092-08-9,19640-64-3
dl-3-methoxy-13β-ethylgona-2,5(10)-dien-17-one

Guidance literature:: Multi-step reaction with 5 steps

1: 80 percent NaH, Et₃N / 1,2-dimethoxy-ethane; paraffin / 1.) 3.5 h, reflux; 2.) 40 min

2: 1.) 2,4,6-trimethylphenol, pyridine; 2.) oxalic acid / 1.) methylcyclohexane, 13.5 h, 98 deg C, irradiation

3: 99 percent / LiAlH₄ / diethyl ether

4: 62 percent / K, aniline, NH₃ / tetrahydrofuran / 1 h

5: 76 percent / 2-butanone, aluminium isopropylate, mol. sieve / benzene

With pyridine; lithium aluminium tetrahydride; molecular sieve; Mesitol; ammonia; oxalic acid; aluminum isopropoxide; sodium hydride; triethylamine; aniline; butanone; In tetrahydrofuran; 1,2-dimethoxyethane; diethyl ether; paraffin; benzene;
DOI:10.1002/hlca.19850680430

Reference yield:

: 848-05-5,19882-75-8
(+/-)-13-Ethyl-3-methoxygona-1,3,5⁽¹⁰⁾,9⁽¹¹⁾-tetraen-17-on

: 2322-77-2,6236-40-4,17092-08-9,19640-64-3
dl-3-methoxy-13β-ethylgona-2,5(10)-dien-17-one

Guidance literature:: Multi-step reaction with 3 steps

1: 99 percent / LiAlH₄ / diethyl ether

2: 62 percent / K, aniline, NH₃ / tetrahydrofuran / 1 h

3: 76 percent / 2-butanone, aluminium isopropylate, mol. sieve / benzene

With lithium aluminium tetrahydride; molecular sieve; ammonia; aluminum isopropoxide; aniline; butanone; In tetrahydrofuran; diethyl ether; benzene;
DOI:10.1002/hlca.19850680430