Methyl 2-amino-2-benzyl-3-phenylpropanoate

Base Information

Chemical Name:Methyl 2-amino-2-benzyl-3-phenylpropanoate
CAS No.:137582-40-2
Molecular Formula:C17H19NO2
Molecular Weight:269.343
Hs Code.:2922499990
DSSTox Substance ID:DTXSID00445477
Wikidata:Q72486711
Mol file:137582-40-2.mol

Synonyms:methyl 2-amino-2-benzyl-3-phenylpropanoate;137582-40-2;Phenylalanine, alpha-(phenylmethyl)-, methyl ester;SCHEMBL7514054;DTXSID00445477;AKOS005146014;FT-0645799;EN300-205417;A807279

Suppliers and Price of Methyl 2-amino-2-benzyl-3-phenylpropanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
Methyl2-amino-2-benzyl-3-phenylpropanoate 95
1g
$ 1467.00

American Custom Chemicals Corporation
METHYL 2-AMINO-2-BENZYL-3-PHENYLPROPANOATE 95.00%
5G
$ 2246.48

American Custom Chemicals Corporation
METHYL 2-AMINO-2-BENZYL-3-PHENYLPROPANOATE 95.00%
1G
$ 1033.73

Total 13 raw suppliers

Chemical Property of Methyl 2-amino-2-benzyl-3-phenylpropanoate

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Refractive Index:1.577
Boiling Point:389.269 °C at 760 mmHg
Flash Point:225.27 °C
PSA：52.32000
Density:1.124 g/cm³
LogP:3.04260
XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:269.141578849
Heavy Atom Count:20
Complexity:284

Purity/Quality:

97% ^*data from raw suppliers

Methyl2-amino-2-benzyl-3-phenylpropanoate 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C(CC1=CC=CC=C1)(CC2=CC=CC=C2)N

Technology Process of Methyl 2-amino-2-benzyl-3-phenylpropanoate

There total 6 articles about Methyl 2-amino-2-benzyl-3-phenylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 199184-30-0
N-[1-(methoxycarbonyl)-1-benzyl-2-phenylethyl]benzophenone imine

: 137582-40-2
methyl (3-phenyl-2-amino-2-benzyl)propanoate

Guidance literature:: With hydrogenchloride; In diethyl ether; dichloromethane; water; at 20 ℃;
DOI:10.1021/jo016330z

Reference yield:

: C₂₄H₂₂ClNO₂

: 137582-40-2
methyl (3-phenyl-2-amino-2-benzyl)propanoate

Guidance literature:: With citric acid; In tetrahydrofuran; at 20 ℃; for 3h;
DOI:10.1002/chem.202102411

Reference yield:

: 100-39-0
benzyl bromide

: 137582-40-2
methyl (3-phenyl-2-amino-2-benzyl)propanoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: KHMDS / tetrahydrofuran / 1 h / -78 °C

1.2: 72 percent / tetrahydrofuran / -78 - 20 °C

2.1: 66 percent / HCl / diethyl ether; CH₂Cl₂; H₂O / 20 °C

With hydrogenchloride; potassium hexamethylsilazane; In tetrahydrofuran; diethyl ether; dichloromethane; water;
DOI:10.1021/jo016330z