(3Z)-3-[2-(1H-indol-3-yl)-2-oxoethylidene]-1H-indol-2-one

Base Information

Chemical Name:(3Z)-3-[2-(1H-indol-3-yl)-2-oxoethylidene]-1H-indol-2-one
CAS No.:70452-34-5
Molecular Formula:C18H12N2O2
Molecular Weight:288.305
Hs Code.:
NSC Number:236606
DSSTox Substance ID:DTXSID40420349
Wikidata:Q82231599

Synonyms:NSC236606;70452-34-5;DTXSID40420349;NSC-236606

Suppliers and Price of (3Z)-3-[2-(1H-indol-3-yl)-2-oxoethylidene]-1H-indol-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of (3Z)-3-[2-(1H-indol-3-yl)-2-oxoethylidene]-1H-indol-2-one

Chemical Property:

Vapor Pressure:6.76E-14mmHg at 25°C
Boiling Point:590°Cat760mmHg
Flash Point:310.6°C
Density:1.44g/cm³
XLogP3:2.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:288.089877630
Heavy Atom Count:22
Complexity:513

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=CN2)C(=O)C=C3C4=CC=CC=C4NC3=O
Isomeric SMILES:C1=CC=C2C(=C1)C(=CN2)C(=O)/C=C\3/C4=CC=CC=C4NC3=O

Technology Process of (3Z)-3-[2-(1H-indol-3-yl)-2-oxoethylidene]-1H-indol-2-one

There total 5 articles about (3Z)-3-[2-(1H-indol-3-yl)-2-oxoethylidene]-1H-indol-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 70452-29-8
3-hydroxy-3-(2-indol-3-yl-2-oxo-ethyl)-1,3-dihydro-indol-2-one

: 70452-34-5
3-(2-indol-3-yl-2-oxo-ethylidene)-1,3-dihydro-indol-2-one

Guidance literature:: With hydrogenchloride; In ethanol; water; at 60 ℃; for 2h;
DOI:10.1016/j.bmcl.2017.06.019

Reference yield:

: 91-56-5,1186480-61-4,84788-92-1
indole-2,3-dione

: 70452-34-5
3-(2-indol-3-yl-2-oxo-ethylidene)-1,3-dihydro-indol-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: diethylamine / ethanol

2: acetic acid; hydrogenchloride / water / 0.5 h / 80 °C

With hydrogenchloride; acetic acid; diethylamine; In ethanol; water; 1: |Aldol Condensation;
DOI:10.3390/molecules25051124

Reference yield:

: 703-80-0
3-acetylindole

: 70452-34-5
3-(2-indol-3-yl-2-oxo-ethylidene)-1,3-dihydro-indol-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: diethylamine / ethanol

2: acetic acid; hydrogenchloride / water / 0.5 h / 80 °C

With hydrogenchloride; acetic acid; diethylamine; In ethanol; water; 1: |Aldol Condensation;
DOI:10.3390/molecules25051124