Benzoic acid,6-hydroxy-3-[5-hydroxy-2-(methoxycarbonyl)-3-(3-oxopentyl)phenoxy]-4-methoxy-2-pentyl-

Base Information

Chemical Name:Benzoic acid,6-hydroxy-3-[5-hydroxy-2-(methoxycarbonyl)-3-(3-oxopentyl)phenoxy]-4-methoxy-2-pentyl-
CAS No.:101910-68-3
Molecular Formula:C₂₆H₃₂O₉
Molecular Weight:488.535
Hs Code.:
Mol file:101910-68-3.mol

Synonyms:Epiphorellicacid 2

Suppliers and Price of Benzoic acid,6-hydroxy-3-[5-hydroxy-2-(methoxycarbonyl)-3-(3-oxopentyl)phenoxy]-4-methoxy-2-pentyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of Benzoic acid,6-hydroxy-3-[5-hydroxy-2-(methoxycarbonyl)-3-(3-oxopentyl)phenoxy]-4-methoxy-2-pentyl-

Chemical Property:

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Benzoic acid,6-hydroxy-3-[5-hydroxy-2-(methoxycarbonyl)-3-(3-oxopentyl)phenoxy]-4-methoxy-2-pentyl-

There total 24 articles about Benzoic acid,6-hydroxy-3-[5-hydroxy-2-(methoxycarbonyl)-3-(3-oxopentyl)phenoxy]-4-methoxy-2-pentyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 24131-31-5
3,5-dibenzyloxybenzyl alcohol

: 101910-68-3
epiphorellic acid 2

Guidance literature:: Multi-step reaction with 17 steps

1: 95 percent / thionyl chloride, pyridine / CH₂Cl₂ / 3 h / Ambient temperature

2: 88 percent / dimethylformamide / 7 h / Ambient temperature

3: 91 percent / 30percent aq. sodium hydroxide / methanol / 72 h / Heating

4: 95 percent / potassium carbonate / acetone / 3 h / Heating

5: 95 percent / lithium aluminium hydride / diethyl ether / 2 h / Heating

6: 85 percent / pyridine / CHCl₃ / 3 h / 0 °C

7: 94 percent / 1,2-dimethoxyethane / dimethylsulfoxide / 18 h / Ambient temperature

8: 81 percent / ether / benzene / 1 h / Ambient temperature; aq. hydrochloric acid, ethyl acetate, 16 h

9: trifluoroacetic anhydride / nitromethane / 1.5 h / 0 °C

10: H₂, conc. hydrichloric acid (4 drops) / 10percent palladized charcoal / ethyl acetate

11: 53 percent / potassium hydrogen carbonate / dimethylformamide / 14 h / Ambient temperature

12: 52 percent / potassium hexacyanoferrate(III), potassium carbonate / H₂O; dioxane / 0.17 h

13: 83 percent / various solvent(s) / 0.17 h / Heating

14: 80 percent / potassium carbonate / dimethylformamide / Ambient temperature

15: 73 percent / sodium methoxide / methanol / 3 h / Ambient temperature

16: 95 percent / potassium carbonate / dimethylformamide / 5 h / Ambient temperature

17: 1.) boron trichloride, 2.) H₂, conc. hydrochloric acid (1 drop) / 10percent palladized charcoal / 1.) dichloromethane, -10 deg C, 0.5 h, 2.) ethyl acetate

With pyridine; hydrogenchloride; sodium hydroxide; lithium aluminium tetrahydride; 1,2-dimethoxyethane; thionyl chloride; diethyl ether; hydrogen; sodium methylate; boron trichloride; potassium carbonate; potassium hydrogencarbonate; trifluoroacetic anhydride; potassium hexacyanoferrate(III); palladium on activated charcoal; In 1,4-dioxane; methanol; diethyl ether; nitromethane; dichloromethane; chloroform; water; dimethyl sulfoxide; ethyl acetate; N,N-dimethyl-formamide; acetone; benzene;

Reference yield:

: 58016-28-7
methyl 2,6-dihydroxy-6-pentylbenzoate

: 101910-68-3
epiphorellic acid 2

Guidance literature:: Multi-step reaction with 15 steps

1: 77 percent / potassium carbonate / acetone / 24 h / Heating

2: 89 percent / potassium carbonate / acetone / Heating

3: 80 percent / potassium hydroxide / dimethylsulfoxide; H₂O / 16 h / 100 °C

4: 83 percent / potassium carbonate / acetone / Heating

5: 100 percent / phosphoryl chloride / 24 h / 70 °C

6: 84 percent / sodium chlorite, sulphamic acid / H₂O; dioxane / 0.67 h

7: trifluoroacetic anhydride / nitromethane / 1.5 h / 0 °C

8: H₂, conc. hydrichloric acid (4 drops) / 10percent palladized charcoal / ethyl acetate

9: 53 percent / potassium hydrogen carbonate / dimethylformamide / 14 h / Ambient temperature

10: 52 percent / potassium hexacyanoferrate(III), potassium carbonate / H₂O; dioxane / 0.17 h

11: 83 percent / various solvent(s) / 0.17 h / Heating

12: 80 percent / potassium carbonate / dimethylformamide / Ambient temperature

13: 73 percent / sodium methoxide / methanol / 3 h / Ambient temperature

14: 95 percent / potassium carbonate / dimethylformamide / 5 h / Ambient temperature

15: 1.) boron trichloride, 2.) H₂, conc. hydrochloric acid (1 drop) / 10percent palladized charcoal / 1.) dichloromethane, -10 deg C, 0.5 h, 2.) ethyl acetate

With hydrogenchloride; potassium hydroxide; sodium chlorite; aminosulfonic acid; hydrogen; sodium methylate; boron trichloride; potassium carbonate; potassium hydrogencarbonate; trifluoroacetic anhydride; potassium hexacyanoferrate(III); trichlorophosphate; palladium on activated charcoal; In 1,4-dioxane; methanol; nitromethane; water; dimethyl sulfoxide; ethyl acetate; N,N-dimethyl-formamide; acetone;

Reference yield:

: 2732-96-9
3,5-dibenzyloxyphenylacetic acid

: 101910-68-3
epiphorellic acid 2

Guidance literature:: Multi-step reaction with 14 steps

1: 95 percent / potassium carbonate / acetone / 3 h / Heating

2: 95 percent / lithium aluminium hydride / diethyl ether / 2 h / Heating

3: 85 percent / pyridine / CHCl₃ / 3 h / 0 °C

4: 94 percent / 1,2-dimethoxyethane / dimethylsulfoxide / 18 h / Ambient temperature

5: 81 percent / ether / benzene / 1 h / Ambient temperature; aq. hydrochloric acid, ethyl acetate, 16 h

6: trifluoroacetic anhydride / nitromethane / 1.5 h / 0 °C

7: H₂, conc. hydrichloric acid (4 drops) / 10percent palladized charcoal / ethyl acetate

8: 53 percent / potassium hydrogen carbonate / dimethylformamide / 14 h / Ambient temperature

9: 52 percent / potassium hexacyanoferrate(III), potassium carbonate / H₂O; dioxane / 0.17 h

10: 83 percent / various solvent(s) / 0.17 h / Heating

11: 80 percent / potassium carbonate / dimethylformamide / Ambient temperature

12: 73 percent / sodium methoxide / methanol / 3 h / Ambient temperature

13: 95 percent / potassium carbonate / dimethylformamide / 5 h / Ambient temperature

14: 1.) boron trichloride, 2.) H₂, conc. hydrochloric acid (1 drop) / 10percent palladized charcoal / 1.) dichloromethane, -10 deg C, 0.5 h, 2.) ethyl acetate

With pyridine; hydrogenchloride; lithium aluminium tetrahydride; 1,2-dimethoxyethane; diethyl ether; hydrogen; sodium methylate; boron trichloride; potassium carbonate; potassium hydrogencarbonate; trifluoroacetic anhydride; potassium hexacyanoferrate(III); palladium on activated charcoal; In 1,4-dioxane; methanol; diethyl ether; nitromethane; chloroform; water; dimethyl sulfoxide; ethyl acetate; N,N-dimethyl-formamide; acetone; benzene;