3-{[4-(2-Methoxyphenyl)-1-piperazinyl]carbonyl}bicyclo[2.2.1]hept-5-ene-2-carboxylic acid

Base Information

Chemical Name:3-{[4-(2-Methoxyphenyl)-1-piperazinyl]carbonyl}bicyclo[2.2.1]hept-5-ene-2-carboxylic acid
CAS No.:5703-07-1
Molecular Formula:C20H24N2O4
Molecular Weight:356.4156
Hs Code.:
DSSTox Substance ID:DTXSID50386427

Synonyms:5703-07-1;3-{[4-(2-methoxyphenyl)-1-piperazinyl]carbonyl}bicyclo[2.2.1]hept-5-ene-2-carboxylic acid;3-[4-(2-METHOXYPHENYL)PIPERAZINE-1-CARBONYL]BICYCLO[2.2.1]HEPT-5-ENE-2-CARBOXYLIC ACID;CBMicro_028807;Cambridge id 5703071;Oprea1_657951;DTXSID50386427;XETXTEAPMQOLHX-UHFFFAOYSA-N;STK375496;AKOS001691128;BIM-0028802.P001;EU-0016525;AB00094026-01;AK-968/11987351;3-{[4-(2-methoxyphenyl)piperazin-1-yl]carbonyl}bicyclo[2.2.1]hept-5-ene-2-carboxylic acid

Suppliers and Price of 3-{[4-(2-Methoxyphenyl)-1-piperazinyl]carbonyl}bicyclo[2.2.1]hept-5-ene-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-{[4-(2-Methoxyphenyl)-1-piperazinyl]carbonyl}bicyclo[2.2.1]hept-5-ene-2-carboxylic acid

Chemical Property:

Vapor Pressure:3.25E-15mmHg at 25°C
Boiling Point:599.4°Cat760mmHg
Flash Point:316.3°C
Density:1.296g/cm³
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:356.17360725
Heavy Atom Count:26
Complexity:584

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC=C1N2CCN(CC2)C(=O)C3C4CC(C3C(=O)O)C=C4

Technology Process of 3-{[4-(2-Methoxyphenyl)-1-piperazinyl]carbonyl}bicyclo[2.2.1]hept-5-ene-2-carboxylic acid

There total 5 articles about 3-{[4-(2-Methoxyphenyl)-1-piperazinyl]carbonyl}bicyclo[2.2.1]hept-5-ene-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5703-06-0
2-(5-methoxy-2,4-dimethyl-phenacyl)-3-methyl-succinic acid

: 5703-07-1
2-(5-methoxy-2,4-dimethyl-phenethyl)-3-methyl-succinic acid

Guidance literature:: With hydrogenchloride; amalgamated zinc;
DOI:10.1039/jr9470000533

Reference yield:

: 6738-23-4
2,4-dimethylanisole

: 5703-07-1
2-(5-methoxy-2,4-dimethyl-phenethyl)-3-methyl-succinic acid

Guidance literature:: Multi-step reaction with 5 steps

1: aluminium chloride; petroleum ether

2: hydrogen chloride; ethanol

3: benzene

4: methanol. KOH-solution

5: amalgamated zinc; aqueous hydrochloric acid

With hydrogenchloride; potassium hydroxide; aluminium trichloride; amalgamated zinc; ethanol; Petroleum ether; benzene;
DOI:10.1039/jr9470000533

Reference yield:

: 4-oxo-4-(5-methoxy-2,4-dimethyl-phenyl)-trans-crotonic acid

: 5703-07-1
2-(5-methoxy-2,4-dimethyl-phenethyl)-3-methyl-succinic acid

Guidance literature:: Multi-step reaction with 4 steps

1: hydrogen chloride; ethanol

2: benzene

3: methanol. KOH-solution

4: amalgamated zinc; aqueous hydrochloric acid

With hydrogenchloride; potassium hydroxide; amalgamated zinc; ethanol; benzene;
DOI:10.1039/jr9470000533