2-(Dimethylamino)-2-ethyl-1-hydroxycyclopentyl phenylacetate--hydrogen chloride (1/1)

Base Information

Chemical Name:2-(Dimethylamino)-2-ethyl-1-hydroxycyclopentyl phenylacetate--hydrogen chloride (1/1)
CAS No.:60452-44-0
Molecular Formula:C₁₇H₂₅NO₃*ClH
Molecular Weight:327.851
Hs Code.:
DSSTox Substance ID:DTXSID60975861

Synonyms:DTXSID60975861;2-(Dimethylamino)-2-ethyl-1-hydroxycyclopentyl phenylacetate--hydrogen chloride (1/1);Benzeneacetic acid, ?-(1-hydroxycyclopentyl)-, 2-(dimethylamino)ethyl ester, hydrochloride, (-)-

Suppliers and Price of 2-(Dimethylamino)-2-ethyl-1-hydroxycyclopentyl phenylacetate--hydrogen chloride (1/1)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 2-(Dimethylamino)-2-ethyl-1-hydroxycyclopentyl phenylacetate--hydrogen chloride (1/1)

Chemical Property:

Vapor Pressure:4.9E-07mmHg at 25°C
Boiling Point:409.7°Cat760mmHg
Flash Point:201.5°C
Density:g/cm³
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:327.1601214
Heavy Atom Count:22
Complexity:365

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1(CCCC1(O)OC(=O)CC2=CC=CC=C2)N(C)C.Cl

Technology Process of 2-(Dimethylamino)-2-ethyl-1-hydroxycyclopentyl phenylacetate--hydrogen chloride (1/1)

There total 3 articles about 2-(Dimethylamino)-2-ethyl-1-hydroxycyclopentyl phenylacetate--hydrogen chloride (1/1) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 512-15-2,744995-89-9,749152-65-6,204990-63-6
Cyclopentolate

: 5870-29-1,60452-44-0,60452-46-2
cyclopentolate hydrochloride

Guidance literature:: With hydrogenchloride; In methanol; tert-butyl methyl ether;

Reference yield:

: 103-82-2
phenylacetic acid

: 5870-29-1,60452-44-0,60452-46-2
cyclopentolate hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1.1: lithium diisopropyl amide / tetrahydrofuran / 1 h / 0 °C / Inert atmosphere

1.2: 10 h / -60 - 20 °C / Inert atmosphere

2.1: potassium carbonate / ethyl acetate / 0.5 h

2.2: 1 h / 60 °C

3.1: hydrogenchloride / tert-butyl methyl ether; methanol

With hydrogenchloride; potassium carbonate; lithium diisopropyl amide; In tetrahydrofuran; methanol; tert-butyl methyl ether; ethyl acetate;

Reference yield:

: 120-92-3
cyclopentanone

: 5870-29-1,60452-44-0,60452-46-2
cyclopentolate hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1.1: lithium diisopropyl amide / tetrahydrofuran / 1 h / 0 °C / Inert atmosphere

1.2: 10 h / -60 - 20 °C / Inert atmosphere

2.1: potassium carbonate / ethyl acetate / 0.5 h

2.2: 1 h / 60 °C

3.1: hydrogenchloride / tert-butyl methyl ether; methanol

With hydrogenchloride; potassium carbonate; lithium diisopropyl amide; In tetrahydrofuran; methanol; tert-butyl methyl ether; ethyl acetate;