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Cyclopentolate

Base Information
  • Chemical Name:Cyclopentolate
  • CAS No.:512-15-2
  • Molecular Formula:C17H25NO3
  • Molecular Weight:291.39
  • Hs Code.:2922509090
  • European Community (EC) Number:208-136-4
  • UNII:I76F4SHP7J
  • DSSTox Substance ID:DTXSID3048528
  • Nikkaji Number:J6.274J,J264.904G,J264.905E
  • Wikipedia:Cyclopentolate
  • Wikidata:Q867332
  • NCI Thesaurus Code:C61693
  • RXCUI:3001
  • Pharos Ligand ID:WWFJVTM14DNX
  • Metabolomics Workbench ID:145707
  • ChEMBL ID:CHEMBL1201338
  • Mol file:512-15-2.mol
Cyclopentolate

Synonyms:Cyclogyl;Cyclopentolate

Suppliers and Price of Cyclopentolate
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • Cyclopentolate
  • 25mg
  • $ 200.00
  • Crysdot
  • 2-(Dimethylamino)ethyl2-(1-hydroxycyclopentyl)-2-phenylacetate 97%
  • 250mg
  • $ 452.00
  • Chemenu
  • 2-(Dimethylamino)ethyl2-(1-hydroxycyclopentyl)-2-phenylacetate 97%
  • 250mg
  • $ 426.00
  • Biosynth Carbosynth
  • Cyclopentolate
  • 50 mg
  • $ 200.00
  • Biosynth Carbosynth
  • Cyclopentolate
  • 25 mg
  • $ 125.00
  • Biosynth Carbosynth
  • Cyclopentolate
  • 10 mg
  • $ 60.00
  • Biosynth Carbosynth
  • Cyclopentolate
  • 5 mg
  • $ 40.00
  • Biosynth Carbosynth
  • Cyclopentolate
  • 100 mg
  • $ 350.00
  • American Custom Chemicals Corporation
  • CYCLOPENTOLATE 95.00%
  • 25MG
  • $ 225.75
  • American Custom Chemicals Corporation
  • CYCLOPENTOLATE 95.00%
  • 1G
  • $ 1206.69
Total 33 raw suppliers
Chemical Property of Cyclopentolate
Chemical Property:
  • Vapor Pressure:1.91E-07mmHg at 25°C 
  • Refractive Index:1.555 
  • Boiling Point:409.7 °C at 760 mmHg 
  • PKA:pKa 7.93(H2O ) (Uncertain) 
  • Flash Point:201.5 °C 
  • PSA:49.77000 
  • Density:1.136 g/cm3 
  • LogP:2.18010 
  • XLogP3:2.7
  • Hydrogen Bond Donor Count:1
  • Hydrogen Bond Acceptor Count:4
  • Rotatable Bond Count:7
  • Exact Mass:291.18344366
  • Heavy Atom Count:21
  • Complexity:331
Purity/Quality:

99.9% *data from raw suppliers

Cyclopentolate *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:CN(C)CCOC(=O)C(C1=CC=CC=C1)C2(CCCC2)O
  • Recent ClinicalTrials:Cycloplegic Refraction Among Children
  • Recent EU Clinical Trials:Prospective, open-label, randomised, single-centre, two-arm, parallel-group, cross-over controlled clinical study, phase 4, to investigate the efficacy of tropicamid 0.5% eyedrops compared to cyclopentolat 0.5% eyedrops for cycloplegia for objective refraction measurement of the eye in 4- to 6-year old children
  • Recent NIPH Clinical Trials:Examination of the nearsighted progress depression effect of the low-concentrated atropine in the Japanese primary schoolchild
  • Uses Cyclopentolate is an effective mydriatic and cycloplegic that begins to act very quickly and has a relatively short duration. It is used also in ophthalmoscopy for causing pre-operational mydriasis. thalidomide derivative for multiple myeloma and myelodysplastic syndromes Cyclopentolate is a muscarinic antagonist. It is used in eye drops to dilate the eyes and prevent them from refocusing making the eyes more sensitive to light and may cause blurring.
  • Therapeutic Function Anticholinergic (ophthalmic)
Technology Process of Cyclopentolate

There total 4 articles about Cyclopentolate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
α-(1-Hydroxycyclopentyl)phenylessigsaeure; With potassium carbonate; In ethyl acetate; for 0.5h;
(2-chloroethyl)dimethylamine hydrochloride; In ethyl acetate; at 60 ℃; for 1h; Solvent; Reagent/catalyst; Temperature;
Guidance literature:
Multi-step reaction with 2 steps
1.1: lithium diisopropyl amide / tetrahydrofuran / 1 h / 0 °C / Inert atmosphere
1.2: 10 h / -60 - 20 °C / Inert atmosphere
2.1: potassium carbonate / ethyl acetate / 0.5 h
2.2: 1 h / 60 °C
With potassium carbonate; lithium diisopropyl amide; In tetrahydrofuran; ethyl acetate;
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