3,5-Dimethyl-1H-pyrazol-4-amine

Base Information

• Chemical Name: 3,5-Dimethyl-1H-pyrazol-4-amine
• CAS No.: 5272-86-6
• Molecular Formula: C5H9 N3
• Molecular Weight: 111.147
• Hs Code.: 2933199090
• European Community (EC) Number: 226-095-0
• DSSTox Substance ID: DTXSID10200690
• Nikkaji Number: J297.972A
• Wikidata: Q83073840
• Mol file: 5272-86-6.mol

Synonyms:3,5-Dimethyl-1H-pyrazol-4-amine;5272-86-6;3,5-Dimethyl-1H-pyrazol-4-ylamine;4-Amino-3,5-dimethylpyrazole;Pyrazole, 4-amino-3,5-dimethyl-;1H-Pyrazol-4-amine, 3,5-dimethyl-;BRN 0108529;4-Amino-3,5-dimethyl-pyrazol;EINECS 226-095-0;MFCD00187666;5-25-09-00510 (Beilstein Handbook Reference);4-ylamine;SCHEMBL4889090;DTXSID10200690;3,5-DIMETHYL-1HPYRAZOL-;HMS1648N03;4-Amino-3,5-dimethyl-1H-pyrazole;BBL005485;STK255768;AKOS000104443;DL-0069;SDCCGMLS-0065490.P001;3,5-Dimethyl-1H-pyrazol-4-ylamine #;BP-10252;SY079005;LS-128013;BB 0217096;CS-0453349;EU-0066993;FT-0676660;EN300-08565;A870921;J-510924;J-511342;Z56761496;F0266-0921;F1011-0264;272-86-6

Chemical Property of 3,5-Dimethyl-1H-pyrazol-4-amine

Chemical Property:

• Vapor Pressure: 0.0011mmHg at 25°C
• Melting Point: 204-205 °C
• Boiling Point: 300.7°Cat760mmHg
• PKA: 18.82±0.50(Predicted)
• Flash Point: 161°C
• PSA: 54.70000
• Density: 1.16g/cm³
• LogP: 1.18990
• Storage Temp.: 2-8°C
• XLogP3: 0.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 111.079647300
• Heavy Atom Count: 8
• Complexity: 83.7

Purity/Quality:

97% ^*data from raw suppliers

3,5-Dimethyl-1H-pyrazol-4-amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C(=NN1)C)N

Technology Process of 3,5-Dimethyl-1H-pyrazol-4-amine

There total 11 articles about 3,5-Dimethyl-1H-pyrazol-4-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

→ 4-amino-3,5-dimethyl-1H-pyrazole (5272-86-6)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In methanol; at 30 ℃; under 6000.6 - 7500.75 Torr;

Reference yield: 88.0%

Isonitrosoacetylacetone (29917-12-2) → 4-amino-3,5-dimethyl-1H-pyrazole (5272-86-6)

Guidance literature:

With hydrazine hydrate; In ethanol; at 80 ℃; for 3h;

Reference yield: 86.0%

3,5-dimethyl-4-nitro-1H-pyrazole (14531-55-6) → 4-amino-3,5-dimethyl-1H-pyrazole (5272-86-6)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In ethanol; for 6h; under 2250.23 Torr; Autoclave;

upstream raw materials:

3,5-dimethyl-4-nitrosopyrazole

3,5-dimethyl-4-nitro-1H-pyrazole

ethanol

hydrazine hydrate

Downstream raw materials:

N-(3,5-dimethyl-1H-pyrazol-4-yl)-benzamide

sulfanilic acid-(3,5-dimethyl-1H-pyrazol-4-ylamide)

4-iodo-3,5-dimethyl-1H-pyrazole

4,4'-azobis(3,5-dimethyl-1H-pyrazole)