n-(4-Hydroxyphenyl)-n-methylbenzamide

Base Information

Chemical Name:n-(4-Hydroxyphenyl)-n-methylbenzamide
CAS No.:70489-16-6
Molecular Formula:C14H13NO2
Molecular Weight:227.2585
Hs Code.:
NSC Number:14700
DSSTox Substance ID:DTXSID10279942
Wikidata:Q82012901
Mol file:70489-16-6.mol

Synonyms:n-(4-hydroxyphenyl)-n-methylbenzamide;70489-16-6;NSC 14700;NSC14700;DTXSID10279942;NSC-14700;AKOS009162036

Suppliers and Price of n-(4-Hydroxyphenyl)-n-methylbenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of n-(4-Hydroxyphenyl)-n-methylbenzamide

Chemical Property:

Vapor Pressure:1.46E-07mmHg at 25°C
Boiling Point:417.5°Cat760mmHg
Flash Point:206.3°C
PSA：40.54000
Density:1.226g/cm³
LogP:2.66880
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:227.094628657
Heavy Atom Count:17
Complexity:253

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C1=CC=C(C=C1)O)C(=O)C2=CC=CC=C2

Technology Process of n-(4-Hydroxyphenyl)-n-methylbenzamide

There total 5 articles about n-(4-Hydroxyphenyl)-n-methylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 90446-72-3
N-[4-(tert-Butyl-dimethyl-silanyloxy)-phenyl]-N-methyl-benzamide

: 70489-16-6
N-methyl-N-(p-hydroxyphenyl)benzamide

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 0 - 20 ℃; for 1h;
DOI:10.1021/jm00381a003

Reference yield:

: 150-75-4
N-methyl-p-aminophenol

: 70489-16-6
N-methyl-N-(p-hydroxyphenyl)benzamide

Guidance literature:: Multi-step reaction with 3 steps

1: imidazole / dimethylformamide / 5 h / 55 °C

2: Et₃N / dioxane / 18 h / 0 - 20 °C

3: tetra-n-butylammonium fluoride / tetrahydrofuran / 1 h / 0 - 20 °C

With 1H-imidazole; tetrabutyl ammonium fluoride; triethylamine; In tetrahydrofuran; 1,4-dioxane; N,N-dimethyl-formamide;
DOI:10.1021/jm00381a003

Reference yield:

: 98-88-4
benzoyl chloride

: 70489-16-6
N-methyl-N-(p-hydroxyphenyl)benzamide

Guidance literature:: Multi-step reaction with 2 steps

1: Et₃N / dioxane / 18 h / 0 - 20 °C

2: tetra-n-butylammonium fluoride / tetrahydrofuran / 1 h / 0 - 20 °C

With tetrabutyl ammonium fluoride; triethylamine; In tetrahydrofuran; 1,4-dioxane;
DOI:10.1021/jm00381a003