Heptanoic acid,2-ethenyl-

Base Information

• Chemical Name: Heptanoic acid,2-ethenyl-
• CAS No.: 4436-85-5
• Mol file: 4436-85-5.mol

Synonyms:

Chemical Property of Heptanoic acid,2-ethenyl-

Chemical Property:

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Heptanoic acid,2-ethenyl-

There total 3 articles about Heptanoic acid,2-ethenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(E)-oct-2-en-1-ol (18409-17-1) + carbon dioxide (124-38-9,18923-20-1) → 3-nonenoic acid (4124-88-3) + 2-vinylheptanoic acid (4436-85-5)

Guidance literature:

With nickel(II) bromide dimethoxyethane; 6,6"-dimethyl-2,2':6',2"-terpyridine; magnesium chloride; zinc; In N,N-dimethyl-formamide; at 40 ℃; for 40h; under 760.051 Torr; Reagent/catalyst; Overall yield = 18 %; diastereoselective reaction; Schlenk technique; Glovebox;

DOI:10.1002/anie.201702857

Reference yield:

(E)-2-octen-1-yl acetate (3913-80-2) + carbon dioxide (124-38-9,18923-20-1) → 3-nonenoic acid (4124-88-3) + 2-vinylheptanoic acid (4436-85-5)

Guidance literature:

With nickel(II) bromide dimethoxyethane; manganese; 6,6'-dimethyl-2,2'-bipyridine; In N,N-dimethyl-formamide; at 40 ℃; for 16h; under 760.051 Torr; Reagent/catalyst; Overall yield = 47 %; Catalytic behavior; Schlenk technique;

DOI:10.1021/ja509077a

Reference yield:

(E)-oct-2-en-1-ol (18409-17-1) → 3-nonenoic acid (4124-88-3) + 2-vinylheptanoic acid (4436-85-5)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 0 - 20 °C

2: nickel(II) bromide dimethoxyethane; 2,2':6',2'':6'',2'''-quaterpyridine; zinc / 16 h / 40 °C / 760.05 Torr / Schlenk technique

With nickel(II) bromide dimethoxyethane; 2,2':6',2'':6'',2'''-quaterpyridine; triethylamine; zinc; In dichloromethane;

DOI:10.1021/ja509077a

upstream raw materials:

(E)-2-octen-1-yl acetate

carbon dioxide

(E)-oct-2-en-1-ol

Refernces

• 1、 Moragas, Toni,Cornella, Josep,Martin, Ruben. "Ligand-controlled regiodivergent Ni-catalyzed reductive carboxylation of allyl esters with CO2". supporting information. p. 17702 - 17705. Retrieved 2015/02/19.