Thiomorpholin-4-amine

Base Information

• Chemical Name: Thiomorpholin-4-amine
• CAS No.: 5997-01-3
• Molecular Formula: C4H10 N2 S
• Molecular Weight: 118.203
• European Community (EC) Number: 892-229-5
• Mol file: 5997-01-3.mol

Synonyms:thiomorpholin-4-amine;5997-01-3;4-amino-tetrahydro-2H-1,4-thiazine;SCHEMBL971418;MFCD18457653;AKOS005213524;LS-09216;CS-0454158;EN300-216204

Chemical Property of Thiomorpholin-4-amine

Chemical Property:

• PSA: 117.08000
• Density: 1.379g/cm³
• LogP: 4.85630
• XLogP3: -0.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 118.05646950
• Heavy Atom Count: 7
• Complexity: 51.7

Purity/Quality:

97% ^*data from raw suppliers

Thiomorpholin-4-amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CSCCN1N

Technology Process of Thiomorpholin-4-amine

There total 2 articles about Thiomorpholin-4-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

N-nitroso thiomorpholine (26541-51-5) → 4-amino-tetrahydro-2H-1,4-thiazine (5997-01-3)

Guidance literature:

With lithium aluminium tetrahydride;

DOI:10.1007/BF00903234

Reference yield:

→ 4-amino-tetrahydro-2H-1,4-thiazine (5997-01-3)

Guidance literature:

Bis-<2-chlor-aethyl>-sulfid, Hydrazinhydrat;

Reference yield: 98.0%

benzaldehyde (100-52-7) + 4-amino-tetrahydro-2H-1,4-thiazine (5997-01-3) → N-Benzylidenamino-thiomorpholin (75161-24-9)

Guidance literature:

With formic acid; In benzene; for 4h; Heating;

DOI:10.1007/BF00903234

upstream raw materials:

N-nitroso thiomorpholine

Downstream raw materials:

[2-(5-nitro-thiophen-2-yl)-thiazol-4-ylmethylene]-thiomorpholin-4-yl-amine

{4-[2-(5-nitro-1-vinyl-1H-imidazol-2-yl)-vinyl]-benzylidene}-thiomorpholin-4-yl-amine

N-Cyclohexylidenamino-thiomorpholin

N-(p-Nitrobenzyliden)-amino-thiomorpholin