9-Benzoyl-N-methyl-2,3,4,9-tetrahydrothiopyrano(2,3-b)indole-4-methylamine oxalate

Base Information

Chemical Name:9-Benzoyl-N-methyl-2,3,4,9-tetrahydrothiopyrano(2,3-b)indole-4-methylamine oxalate
CAS No.:73426-19-4
Molecular Formula:C₂H₂O₄*C₂₀H₂₀N₂OS
Molecular Weight:426.493
Hs Code.:
DSSTox Substance ID:DTXSID90994186

Synonyms:9-Benzoyl-N-methyl-2,3,4,9-tetrahydrothiopyrano(2,3-b)indole-4-methylamine oxalate;9-Benzoyl-4-((methylamino)methyl)-2,3,4,9-tetrahydrothiopyrano(2,3-b)indole oxalate;Thiopyrano(2,3-b)indole, 2,3,4,9-tetrahydro-9-benzoyl-4-((methylamino)methyl)-, oxalate;Thiopyrano(2,3-b)indole-4-methylamine, 2,3,4,9-tetrahydro-9-benzoyl-N-methyl-, oxalate;73426-19-4;DTXSID90994186;C20H20N2OS.C2H2O4;LS-153277;C20-H20-N2-O-S.C2-H2-O4;Oxalic acid--{4-[(methylamino)methyl]-3,4-dihydrothiopyrano[2,3-b]indol-9(2H)-yl}(phenyl)methanone (1/1)

Suppliers and Price of 9-Benzoyl-N-methyl-2,3,4,9-tetrahydrothiopyrano(2,3-b)indole-4-methylamine oxalate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 9-Benzoyl-N-methyl-2,3,4,9-tetrahydrothiopyrano(2,3-b)indole-4-methylamine oxalate

Chemical Property:

Vapor Pressure:8.52E-08mmHg at 25°C
Boiling Point:435.8°Cat760mmHg
Flash Point:217.4°C
Density:g/cm³
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:4
Exact Mass:426.12494298
Heavy Atom Count:30
Complexity:523

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CNCC1CCSC2=C1C3=CC=CC=C3N2C(=O)C4=CC=CC=C4.C(=O)(C(=O)O)O

Technology Process of 9-Benzoyl-N-methyl-2,3,4,9-tetrahydrothiopyrano(2,3-b)indole-4-methylamine oxalate

There total 4 articles about 9-Benzoyl-N-methyl-2,3,4,9-tetrahydrothiopyrano(2,3-b)indole-4-methylamine oxalate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 73425-49-7
4-aminomethyl-2,3,4,9-tetrahydrothiopyrano<2,3-b>indole

: 73426-19-4
(4-Methylaminomethyl-3,4-dihydro-2H-thiopyrano[2,3-b]indol-9-yl)-phenyl-methanone; compound with oxalic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 93 percent / Et₃N / tetrahydrofuran / 1 h / Ambient temperature

2: 1) 50 percent NaH / 1.) oil, DMF, RT, 1 h; 2.) DMF, oil

3: 1) CF₃COOH / 1) 2 h, CH₂Cl₂; 2) acetone

With sodium hydride; triethylamine; trifluoroacetic acid; In tetrahydrofuran;
DOI:10.1248/cpb.32.877

Reference yield:

: 98-88-4
benzoyl chloride

: 73426-19-4
(4-Methylaminomethyl-3,4-dihydro-2H-thiopyrano[2,3-b]indol-9-yl)-phenyl-methanone; compound with oxalic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 1) 50 percent NaH / 1.) oil, DMF, RT, 1 h; 2.) DMF, oil

2: 1) CF₃COOH / 1) 2 h, CH₂Cl₂; 2) acetone

With sodium hydride; trifluoroacetic acid;
DOI:10.1248/cpb.32.877

Reference yield:

: 73425-25-9
4-(N-tert-butoxycarbonyl-N-methylaminomethyl)-2,3,4,9-tetrahydrothiopyrano<2,3-b>indole

: 73426-19-4
(4-Methylaminomethyl-3,4-dihydro-2H-thiopyrano[2,3-b]indol-9-yl)-phenyl-methanone; compound with oxalic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 1) 50 percent NaH / 1.) oil, DMF, RT, 1 h; 2.) DMF, oil

2: 1) CF₃COOH / 1) 2 h, CH₂Cl₂; 2) acetone

With sodium hydride; trifluoroacetic acid;
DOI:10.1248/cpb.32.877