3-(2-Aminoethyl)pyridine

Base Information

• Chemical Name: 3-(2-Aminoethyl)pyridine
• CAS No.: 20173-24-4
• Molecular Formula: C7H10N2
• Molecular Weight: 122.17
• Hs Code.: 29333990
• European Community (EC) Number: 671-720-6
• DSSTox Substance ID: DTXSID70357538
• Nikkaji Number: J663.154A
• Wikidata: Q27454428
• Pharos Ligand ID: NA7K4FMJ7LQV
• ChEMBL ID: CHEMBL1256004
• Mol file: 20173-24-4.mol

Synonyms:20173-24-4;3-(2-Aminoethyl)pyridine;2-(pyridin-3-yl)ethanamine;3-aminoethylpyridine;2-pyridin-3-ylethanamine;3-Pyridineethanamine;3-PYRIDINEETHANEAMINE;2-(Pyridin-3-Yl)Ethan-1-Amine;2-(3-Pyridyl)ethylamine;2-Pyridin-3-yl-ethylamine;MFCD00191604;2-(pyridin-3-yl)ethylamine;CHEMBL1256004;2-(3-PYRIDINYL)ETHANAMINE;2-(3-pyridyl)ethanamine;3-pyridine ethanamine;3-pyridylethylamine;45X;3-(aminoethyl)pyridine;2-pyridin-3-ylethylamine;2-(3-pyridinyl)ethylamine;3-(2-amino-ethyl)pyridine;3-(2-aminoethyl) pyridine;(2-pyridin-3-yl)ethylamine;(2-pyridin-3-ylethyl)amine;2-(3-pyridyl)-ethyl amine;2-(pyridine-3-yl)ethylamine;2-pyridine-3-yl-ethyl amine;SCHEMBL104220;[2-(3-pyridinyl)ethyl]amine;1-amino-2-(3-pyridyl)ethane;DTXSID70357538;NAHHNSMHYCLMON-UHFFFAOYSA-N;AM836;BDBM50417104;STK503684;3-(2-aminoethyl)pyridine, AldrichCPR;AKOS000142456;AB04606;AC-6717;CS-W008641;BS-13034;SY003234;A4399;BB 0241846;FT-0613524;EN300-29225;W-206489;Q27454428;F0001-0713;Z241056524

Chemical Property of 3-(2-Aminoethyl)pyridine

Chemical Property:

• Vapor Pressure: 0.0719mmHg at 25°C
• Refractive Index: 1.5518
• Boiling Point: 228.8 °C at 760 mmHg
• PKA: 9.29±0.10(Predicted)
• Flash Point: 112.8 °C
• PSA: 38.91000
• Density: 1.025 g/cm³
• LogP: 1.28310
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Sensitive.: Air Sensitive
• Water Solubility.: Slightly soluble in water.
• XLogP3: -0.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 122.084398327
• Heavy Atom Count: 9
• Complexity: 73.3

Purity/Quality:

99% ^*data from raw suppliers

2-(Pyridin-3-yl)ethanamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R34:Causes burns.
• Hazard Codes: Xi
• Statements: 34-41-37/38
• Safety Statements: 26-36/37/39-39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CN=C1)CCN
• Uses: 3-(2-Aminoethyl)pyridine has been used in the synthesis of urea.

Technology Process of 3-(2-Aminoethyl)pyridine

There total 2 articles about 3-(2-Aminoethyl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

→ 2-pyridin-3-ylethylamine (20173-24-4) + (4-Methoxy-7-phenyl-benzothiazol-2-yl)-(2-pyridin-2-yl-ethyl)-amine hydrochloride salt

Guidance literature:

Reference yield:

2-amino-3-(pyridin-3-yl)propanoic acid (17470-24-5,28105-69-3,64090-98-8,70702-47-5) → 2-pyridin-3-ylethylamine (20173-24-4)

Guidance literature:

With diphenylamine; at 245 - 250 ℃;

DOI:10.1021/ja01262a018

Reference yield: 98.0%

2-pyridin-3-ylethylamine (20173-24-4) + 4-(4-((1-(tert-butoxycarbonyl)piperidin-4-ylsulfonyl)methyl)-5-methyloxazol-2-yl)benzoic acid → tert-butyl 4-((2-(4-((2-(pyridin-3-yl)ethyl)carbamoyl)phenyl)-5-methyloxazol-4-yl)methylsulfonyl)piperidine-1-carboxylate

Guidance literature:

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In N,N-dimethyl-formamide; at 30 ℃;

upstream raw materials:

2-amino-3-(pyridin-3-yl)propanoic acid

Downstream raw materials:

N-(2-pyridin-3-yl-ethyl)-benzamide

3-pyridinylethanol

N-[3-Methoxy-4-(5-oxazolyl)phenyl]-6-phenyl-N'-[2-(3-pyridinyl)ethyl]-1,3,5-triazine-2,4-diamine