N-Methylciprofloxacin

Base Information

Chemical Name:N-Methylciprofloxacin
CAS No.:86483-46-7
Molecular Formula:C18H20FN3O3
Molecular Weight:345.374
Hs Code.:
DSSTox Substance ID:DTXSID90878316
Nikkaji Number:J728.005J
Wikidata:Q82860332
ChEMBL ID:CHEMBL429961

Synonyms:N-Methylciprofloxacin;CHEMBL429961;SCHEMBL2780752;DTXSID90878316;BDBM50470984;MF-9056;1-cyclopropyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxo-quinoline-3-carboxylic acid;1-cyclopropyl-7-(4-methylpiperazinyl)-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid;1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(4-methyl-1-piperazinyl)-3-quinolinecarboxylic acid

Suppliers and Price of N-Methylciprofloxacin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-Methylciprofloxacin

Chemical Property:

PSA：65.78000
LogP:1.92840
XLogP3:-0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:3
Exact Mass:345.14886967
Heavy Atom Count:25
Complexity:598

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCN(CC1)C2=C(C=C3C(=C2)N(C=C(C3=O)C(=O)O)C4CC4)F

Technology Process of N-Methylciprofloxacin

There total 2 articles about N-Methylciprofloxacin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 85721-33-1,178489-05-9,189257-90-7
ciprofloxacin

: 86483-46-7
N-methylciprofloxacin

Guidance literature:

Reference yield:

: 86393-34-2
2,4-dichloro-5-fluorobenzoyl chloride

: 86483-46-7
N-methylciprofloxacin

Guidance literature:: Multi-step reaction with 4 steps

1: 62 percent / pyridine / dioxane / 1.) 2 h, room temperature, 2.) 1 h, 70 - 80 deg C_.

2: 85 percent / potassium carbonate / dimethylformamide / 2 h / 140 - 150 °C

3: 92 percent / conc. H₂SO₄ / H₂O; acetic acid / 1.5 h / Heating

4: 67 percent / dimethylsulfoxide / 2.5 h / 140 °C

With pyridine; sulfuric acid; potassium carbonate; In 1,4-dioxane; water; acetic acid; dimethyl sulfoxide; N,N-dimethyl-formamide;