EC 3.6.1.1

Base Information

• Chemical Name: EC 3.6.1.1
• CAS No.: 9024-82-2
• Molecular Formula: NULL
• Molecular Weight: 0

Synonyms:Diphosphatase;E.C. 3.6.1.1; Inorg. pyrophosphatase; Inorganic pyrophosphatase; Phospholysinephosphohistidine inorganic pyrophosphate phosphatase; Pyrophosphatase;Pyrophosphate phosphohydrolase

Chemical Property of EC 3.6.1.1

Chemical Property:

• PSA: 0.00000
• LogP: 0.00000
• Storage Temp.: 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

Pyrophosphatase, Inorganic from baker's yeast (S.?cerevisiae) powder, ≥500?units/mg protein (E1%/280) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: Inorganic pyrophosphatase (PPase) is a ubiquitous enzyme catalyzing the reaction PPi + H2O → 2Pi. It plays an important role in protein, RNA, and DNA synthesis.

Refernces

Expanding the pyrimidine diphosphosugar repertoire: The chemoenzymatic synthesis of amino- and acetamidoglucopyranosyl derivatives

10.1002/1521-3773(20010417)40:8<1502::AID-ANIE1502>3.0.CO;2-K

The research focuses on the development of a chemoenzymatic method for the synthesis of aminodeoxy-α-D-glucopyranosyl and acetamidodeoxy-α-D-glucopyranosyl phosphate derivatives, which are important substrates for in vitro glycosylation systems. The researchers utilized Salmonella enterica LT2 α-D-glucopyranosyl phosphate thymidylyltransferase (E. coli) to phosphorylate and convert a range of synthetic substrates, including 1-ethylthio-β-D-pyranoside precursors, into the desired nucleotide sugars. The conclusions drawn from the study highlight the promiscuous nature of E. coli and its ability to accommodate various substrates, with the exception of those with bulky substituents at certain positions. The chemicals used in the process included various sugar phosphates, nucleotide triphosphates (NTPs), inorganic pyrophosphatase, and the enzyme E. coli itself, along with reagents for the synthesis and purification of the sugar phosphates, such as dibenzyl phosphate, sodium azide, and acetic anhydride.

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