1-Butanesulfonamide

Base Information

• Chemical Name: 1-Butanesulfonamide
• CAS No.: 3144-04-5
• Molecular Formula: C4H11NO2S
• Molecular Weight: 137.203
• European Community (EC) Number: 674-861-1
• NSC Number: 26772
• UNII: 934CE25MDC
• DSSTox Substance ID: DTXSID80185364
• Nikkaji Number: J1.743.243E
• Wikidata: Q83056386
• Mol file: 3144-04-5.mol

Synonyms:butane-1-sulfonamide;3144-04-5;1-BUTANESULFONAMIDE;butanesulfonamide;N-Butylsulfonamide;Butansulfamid [German];934CE25MDC;NSC 26772;NSC-26772;BRN 1749709;Butansulfamid;n-butylsulphonamide;1-n-Butanesulfonamide;SCHEMBL2826;Butan-1-sulfonic acid amide;UNII-934CE25MDC;butane-1-sulfonic acid amide;DTXSID80185364;NSC26772;AKOS000143030;FS-4925;LS-45960;CS-0450901;FT-0721252;EN300-30817;J-018429;Z55264566

Chemical Property of 1-Butanesulfonamide

Chemical Property:

• Vapor Pressure: 0.0368mmHg at 25°C
• Boiling Point: 241°Cat760mmHg
• Flash Point: 99.5°C
• Density: 1.15g/cm³
• XLogP3: 0.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 137.05104977
• Heavy Atom Count: 8
• Complexity: 133

Purity/Quality:

99.3% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCS(=O)(=O)N

Technology Process of 1-Butanesulfonamide

There total 7 articles about 1-Butanesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

perfluoro-1-butanesulfonyl fluoride (2386-60-9) → butane-1-sulfonamide (3144-04-5)

Guidance literature:

With ammonia; In acetonitrile;

DOI:10.1016/S0960-894X(98)00387-4

Reference yield: 82.0%

C10H14Cl6N2O6S → butane-1-sulfonamide (3144-04-5)

Guidance literature:

With acetone; zinc; In acetic acid; at 25 ℃; for 2.5h;

DOI:10.1016/S0040-4039(02)00848-1

Reference yield: 44.0%

1-bromo-butane (109-65-9) → butane-1-sulfonamide (3144-04-5)

Guidance literature:

1-bromo-butane; With sodium sulfite; In water; Heating;

With trichlorophosphate; at 130 ℃; for 4h;

With ammonia; In water; acetonitrile; at 0 ℃; for 1h;

DOI:10.1002/hlca.200490148

upstream raw materials:

perfluoro-1-butanesulfonyl fluoride

n-butyllithium

n-butylsulphonyl isocyanate

1-bromo-butane

Downstream raw materials:

(butane-1-sulfonyl)-carbamic acid pentyl ester

N-(phenylcarbamoyl)butane-1-sulfonamide

N-(butane-1-sulfonyl)-N'-p-tolyl-thiourea

N-(butane-1-sulfonyl)-N'-(4-nitro-phenyl)-urea

Refernces

• 1、 Zhong, Dayou,Wu, Di,Zhang, Yan,Lu, Zhiwu,Usman, Muhammad,Liu, Wei,Lu, Xiuqiang,Liu, Wen-Bo. "Synthesis of Sultams and Cyclic N-Sulfonyl Ketimines via Iron-Catalyzed Intramolecular Aliphatic C-H Amidation". supporting information. p. 5808 - 5812. Retrieved 2019/08/26.
• 2、 Kim, Jinho,Stahl, Shannon S.. "Cu-catalyzed aerobic oxidative three-component coupling route to N -sulfonyl amidines via an ynamine intermediate". . p. 2448 - 2454. Retrieved 2015/04/14.