2,19-(Methyleneoxy)androst-4-ene-3,17-dione

Base Information

Chemical Name:2,19-(Methyleneoxy)androst-4-ene-3,17-dione
CAS No.:136182-63-3
Molecular Formula:C₂₀H₂₆O₃
Molecular Weight:314.425
Hs Code.:
DSSTox Substance ID:DTXSID20929289
Nikkaji Number:J492.092I
Wikidata:Q82904126
Pharos Ligand ID:TC7ABN3KFTA7
ChEMBL ID:CHEMBL3754275
Mol file:136182-63-3.mol

Synonyms:2,19-(methyleneoxy)androst-4-ene-3,17-dione;2,19-MOAED

Suppliers and Price of 2,19-(Methyleneoxy)androst-4-ene-3,17-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2,19-(Methyleneoxy)androst-4-ene-3,17-dione

Chemical Property:

Vapor Pressure:5.97E-10mmHg at 25°C
Boiling Point:495.3°Cat760mmHg
Flash Point:218.9°C
PSA：43.37000
Density:1.2g/cm³
LogP:3.32380
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:314.18819469
Heavy Atom Count:23
Complexity:620

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC12CCC3C(C1CCC2=O)CCC4=CC(=O)C5CC34COC5
Isomeric SMILES:C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)CCC4=CC(=O)[C@@H]5C[C@]34COC5

Technology Process of 2,19-(Methyleneoxy)androst-4-ene-3,17-dione

There total 3 articles about 2,19-(Methyleneoxy)androst-4-ene-3,17-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

: 136182-66-6
<<19-<(2-methoxyethoxy)methoxy>androsta-2,4,16-triene-3,17-diyl>bis(oxy)>bis

: 136182-63-3
(4α,10α)-4,19-cyclo-A-dihomo-2-oxaandrost-4b-ene-4a,17-dione

Guidance literature:: With titanium tetrachloride; In dichloromethane; at -20 ℃; for 0.583333h;
DOI:10.1021/jm00095a030

Reference yield:

: 510-64-5
19-hydroxy-4-androstene-3,17-dione

: 136182-63-3
(4α,10α)-4,19-cyclo-A-dihomo-2-oxaandrost-4b-ene-4a,17-dione

Guidance literature:: Multi-step reaction with 3 steps

1: 76 percent / diisopropylethylamine / CH₂Cl₂ / 20 h

2: 1) lithium diisopropylamide / 1) THF, hexane, -20 deg C, 3 min, 2) -20 deg C, 30 min

3: TiCl₄ / CH₂Cl₂ / 0.5 h / -20 °C

With titanium tetrachloride; N-ethyl-N,N-diisopropylamine; lithium diisopropyl amide; In dichloromethane;
DOI:10.1021/jo00045a028

Reference yield:

: 136182-65-5
19-<(2-methoxyethoxy)methoxy>androst-4-ene-3,17-dione

: 136182-63-3
(4α,10α)-4,19-cyclo-A-dihomo-2-oxaandrost-4b-ene-4a,17-dione

Guidance literature:: Multi-step reaction with 2 steps

1: 1) lithium diisopropylamide / 1) THF, hexane, -20 deg C, 3 min, 2) -20 deg C, 30 min

2: TiCl₄ / CH₂Cl₂ / 0.5 h / -20 °C

With titanium tetrachloride; lithium diisopropyl amide; In dichloromethane;
DOI:10.1021/jo00045a028