19-Hydroxyandrost-4-ene-3,17-dione

Base Information Edit

Chemical Name:19-Hydroxyandrost-4-ene-3,17-dione
CAS No.:510-64-5
Molecular Formula:C19H26O3
Molecular Weight:302.414
Hs Code.:29372900
European Community (EC) Number:208-116-5
NSC Number:74233
UNII:A546CQ0584
DSSTox Substance ID:DTXSID80199007,DTXSID90862078
Nikkaji Number:J117.011B
Wikidata:Q27103205
Pharos Ligand ID:P3U1T3UY67DN
Metabolomics Workbench ID:35348
ChEMBL ID:CHEMBL4517318
Mol file:510-64-5.mol

Synonyms:19-HAED;19-hydroxy-4-androstene-3,17-dione;19-hydroxy-4-androstene-3,17-dione, 18O-labeled;19-hydroxyandrost-4-ene-3,17-dione;19-hydroxyandrostenedione

Suppliers and Price of 19-Hydroxyandrost-4-ene-3,17-dione

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
19-Hydroxy-4-androstene-3,17-dione ≥90% (HPLC)
1g
$ 341.00

Sigma-Aldrich
19-Hydroxy-4-androstene-3,17-dione ≥90% (HPLC)
100mg
$ 86.70

Matrix Scientific
19-Hydroxyandrost-4-ene-3,17-dione 95+%
5g
$ 80.00

Matrix Scientific
19-Hydroxyandrost-4-ene-3,17-dione 95+%
100g
$ 850.00

Matrix Scientific
19-Hydroxyandrost-4-ene-3,17-dione 95+%
25g
$ 282.00

Chemenu
19-Hydroxyandrost-4-ene-3,17-dione 95%
25g
$ 266.00

Chemenu
19-Hydroxyandrost-4-ene-3,17-dione 95%
10g
$ 153.00

Chemenu
19-Hydroxyandrost-4-ene-3,17-dione 95%
5g
$ 102.00

AHH
19-Hydroxyandrostendione 98%
5g
$ 440.00

Total 103 raw suppliers

Chemical Property of 19-Hydroxyandrost-4-ene-3,17-dione Edit

Chemical Property:

Appearance/Colour:off-white solid
Vapor Pressure:1.84E-11mmHg at 25°C
Melting Point:168-169 °C(lit.)
Refractive Index:1.571
Boiling Point:485.4 °C at 760 mmHg
PKA:14.90±0.10(Predicted)
Flash Point:261.5 °C
PSA：54.37000
Density:1.19 g/cm³
LogP:3.05980
Storage Temp.:-20°C Freezer
Solubility.:Chloroform (Slightly), Methanol (Slightly)
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:302.18819469
Heavy Atom Count:22
Complexity:563

Purity/Quality:

99% ^*data from raw suppliers

19-Hydroxy-4-androstene-3,17-dione ≥90% (HPLC) ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi,Xn
Statements: 36/37/38-63
Safety Statements: 22-24/25-36/37/39-27-26-36/37

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CC12CCC3C(C1CCC2=O)CCC4=CC(=O)CCC34CO
Isomeric SMILES:C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)CCC4=CC(=O)CC[C@]34CO
Uses A novel substituted estrogen as aromatase inhibitor 19-Hydroxyandrostendione is a novel substituted estrogen as aromatase inhibitor. It induces neuroendocrine trans-differentiation of prostate cancer cells via an ectopic olactory receptor.

Technology Process of 19-Hydroxyandrost-4-ene-3,17-dione

There total 39 articles about 19-Hydroxyandrost-4-ene-3,17-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 968-49-0
19-oxoandrostenedione

: 510-64-5
19-hydroxy-4-androstene-3,17-dione

Guidance literature:: With fungus Gnomonia fructicola; In ethanol; at 24 - 26 ℃; for 120h;
DOI:10.1139/v89-044

Reference yield: 84.0%

: 510-65-6
19-hydroxycortodoxone

: 510-64-5
19-hydroxy-4-androstene-3,17-dione

Guidance literature:: 19-hydroxycortodoxone; With sodium tetrahydroborate; ethanol; In dichloromethane; at 0 ℃; for 1.5h;

With sodium periodate; In water; at 25 ℃; Solvent; Reagent/catalyst; Temperature;