Pyrrolidine, 1-((4-oxo-2-(3,4,5-trimethoxyphenyl)-3(4H)-quinazolinyl)acetyl)-

Base Information

Chemical Name:Pyrrolidine, 1-((4-oxo-2-(3,4,5-trimethoxyphenyl)-3(4H)-quinazolinyl)acetyl)-
CAS No.:83409-08-9
Molecular Formula:C₂₃H₂₅N₃O₅
Molecular Weight:423.469
Hs Code.:
DSSTox Substance ID:DTXSID20232341

Synonyms:BRN 4595666;Pyrrolidine, 1-((4-oxo-2-(3,4,5-trimethoxyphenyl)-3(4H)-quinazolinyl)acetyl)-;1-((4-Oxo-2-(3,4,5-trimethoxyphenyl)-3(4H)-quinazolinyl)acetyl)pyrrolidine;83409-08-9;DTXSID20232341;LS-138065

Suppliers and Price of Pyrrolidine, 1-((4-oxo-2-(3,4,5-trimethoxyphenyl)-3(4H)-quinazolinyl)acetyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Pyrrolidine, 1-((4-oxo-2-(3,4,5-trimethoxyphenyl)-3(4H)-quinazolinyl)acetyl)-

Chemical Property:

Vapor Pressure:1.5E-15mmHg at 25°C
Boiling Point:625.3°Cat760mmHg
Flash Point:332°C
Density:1.29g/cm³
XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:423.17942091
Heavy Atom Count:31
Complexity:679

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=CC(=C1OC)OC)C2=NC3=CC=CC=C3C(=O)N2CC(=O)N4CCCC4

Technology Process of Pyrrolidine, 1-((4-oxo-2-(3,4,5-trimethoxyphenyl)-3(4H)-quinazolinyl)acetyl)-

There total 5 articles about Pyrrolidine, 1-((4-oxo-2-(3,4,5-trimethoxyphenyl)-3(4H)-quinazolinyl)acetyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 123-75-1
pyrrolidine

: 83409-25-0
[4-Oxo-2-(3,4,5-trimethoxy-phenyl)-4H-quinazolin-3-yl]-acetyl chloride

: 83409-08-9
3-(2-Oxo-2-pyrrolidin-1-yl-ethyl)-2-(3,4,5-trimethoxy-phenyl)-3H-quinazolin-4-one

Guidance literature:: In benzene; for 2h; Heating;

Reference yield:

: 40728-74-3
2-(3,4,5-trimethoxyphenyl)-4-H-benzo[d][1,3]oxazin-4-one

: 83409-08-9
3-(2-Oxo-2-pyrrolidin-1-yl-ethyl)-2-(3,4,5-trimethoxy-phenyl)-3H-quinazolin-4-one

Guidance literature:: Multi-step reaction with 3 steps

1: 85 percent / pyridine; H₂O / 10 h / Heating

2: SOCl₂ / benzene / 6 h / Heating

3: 68 percent / benzene / 2 h / Heating

With thionyl chloride; In pyridine; water; benzene;

Reference yield:

: 4521-61-3
3,4,5-Trimethoxybenzoyl chloride

: 83409-08-9
3-(2-Oxo-2-pyrrolidin-1-yl-ethyl)-2-(3,4,5-trimethoxy-phenyl)-3H-quinazolin-4-one

Guidance literature:: Multi-step reaction with 4 steps

1: pyridine / 1) 0-5 deg C 2) 1h, room temperature

2: 85 percent / pyridine; H₂O / 10 h / Heating

3: SOCl₂ / benzene / 6 h / Heating

4: 68 percent / benzene / 2 h / Heating

With pyridine; thionyl chloride; In pyridine; water; benzene;