1,2-dimethyl-3-nitro-1H-pyrrole

Base Information

• Chemical Name: 1,2-dimethyl-3-nitro-1H-pyrrole
• CAS No.: 72083-72-8
• Molecular Formula: C₆H₈N₂O₂
• Molecular Weight: 140.142
• Mol file: 72083-72-8.mol

Synonyms:

Chemical Property of 1,2-dimethyl-3-nitro-1H-pyrrole

Chemical Property:

• Vapor Pressure: 0.0832mmHg at 25°C
• Boiling Point: 233.9°Cat760mmHg
• Flash Point: 95.2°C
• Density: 1.22g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,2-dimethyl-3-nitro-1H-pyrrole

There total 13 articles about 1,2-dimethyl-3-nitro-1H-pyrrole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

4-nitro-5-methyl-1-methylpyrrole-2-carboxylic acid (72795-81-4) → 1,2-Dimethyl-3-nitropyrrole (72083-72-8)

Guidance literature:

With quinoline; copper; at 195 ℃; for 1h;

DOI:10.1039/P19960002277

Reference yield: 82.0%

2-Methyl-3-nitropyrrole (26477-34-9) + methyl iodide (74-88-4) → 1,2-Dimethyl-3-nitropyrrole (72083-72-8)

Guidance literature:

With potassium hydroxide; In dimethyl sulfoxide; for 1h;

DOI:10.1039/P19960002277

Reference yield: 40.0%

2-Methyl-3-nitropyrrole (26477-34-9) + methyl iodide (74-88-4) → 1,2-Dimethyl-3-nitropyrrole (72083-72-8) + 2-Ethyl-1-methyl-3-nitropyrrole

Guidance literature:

With potassium tert-butylate; In dimethyl sulfoxide; for 2h; Ambient temperature;

DOI:10.1039/P19960002277

upstream raw materials:

1,2-dimethylpyrrole

4-nitro-5-methyl-1-methylpyrrole-2-carboxylic acid

ethyl 4-nitro-5-methyl-1-methylpyrrole-2-carboxylate

2-Methyl-3-nitropyrrole

Refernces

• 1、 Skvortsov, I. M.,Astakhova, L. N.. "1-AZABICYCLIC COMPOUNDS. 24. SELECTIVITY OF POSITION OF NITRATION OF 1,2-DIHYDROPYRROLIZINE, 5,6,7,8-TETRAHYDROPYRROCOLINE AND PYRROLE HOMOLOGS". . p. 1189 - 1191. Retrieved 2007/10/02.