2-Buten-1-ol, 4-(2-(((1,1-dimethylethyl)dimethylsilyl)oxy)cyclohexyl)-2-methyl-, (1alpha(E),2beta)-

Base Information

Chemical Name:2-Buten-1-ol, 4-(2-(((1,1-dimethylethyl)dimethylsilyl)oxy)cyclohexyl)-2-methyl-, (1alpha(E),2beta)-
CAS No.:101859-31-8
Molecular Formula:C17H34O2Si
Molecular Weight:298.5362
Hs Code.:

Synonyms:101859-31-8;2-Buten-1-ol, 4-(2-(((1,1-dimethylethyl)dimethylsilyl)oxy)cyclohexyl)-2-methyl-, (1alpha(E),2beta)-

Suppliers and Price of 2-Buten-1-ol, 4-(2-(((1,1-dimethylethyl)dimethylsilyl)oxy)cyclohexyl)-2-methyl-, (1alpha(E),2beta)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of 2-Buten-1-ol, 4-(2-(((1,1-dimethylethyl)dimethylsilyl)oxy)cyclohexyl)-2-methyl-, (1alpha(E),2beta)-

Chemical Property:

Vapor Pressure:2.51E-06mmHg at 25°C
Boiling Point:351°Cat760mmHg
Flash Point:166.1°C
Density:0.92g/cm³
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:6
Exact Mass:298.232806857
Heavy Atom Count:20
Complexity:328

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=CCC1CCCCC1O[Si](C)(C)C(C)(C)C)CO
Isomeric SMILES:C/C(=C\C[C@H]1CCCC[C@@H]1O[Si](C)(C)C(C)(C)C)/CO

Technology Process of 2-Buten-1-ol, 4-(2-(((1,1-dimethylethyl)dimethylsilyl)oxy)cyclohexyl)-2-methyl-, (1alpha(E),2beta)-

There total 5 articles about 2-Buten-1-ol, 4-(2-(((1,1-dimethylethyl)dimethylsilyl)oxy)cyclohexyl)-2-methyl-, (1alpha(E),2beta)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 101859-22-7
(E)-4-[(1S,2R)-2-(tert-Butyl-dimethyl-silanyloxy)-cyclohexyl]-2-methyl-but-2-enoic acid methyl ester

: 101859-31-8
(1R*,2S*,(2E))-2-((tert-butyldimethylsilyl)oxy)cyclohexane-3-methyl-2-buten-4-ol

Guidance literature:: With diisobutylaluminium hydride; In toluene; at -78 - 0 ℃;
DOI:10.1021/jo00362a014

Reference yield:

: 74708-24-0,74708-25-1,90242-33-4,101976-91-4,74629-88-2
(1R*,2S*)-2-hydroxycyclohexane acetonitrile

: 101859-31-8
(1R*,2S*,(2E))-2-((tert-butyldimethylsilyl)oxy)cyclohexane-3-methyl-2-buten-4-ol

Guidance literature:: Multi-step reaction with 4 steps

1: 88 percent / TEA, DMAP / tetrahydrofuran; dimethylformamide

2: 86 percent / dibal / toluene / -78 - 0 °C

3: 90 percent / CHCl₃ / Heating

4: 94 percent / dibal / toluene / -78 - 0 °C

With dmap; TEA; diisobutylaluminium hydride; In tetrahydrofuran; chloroform; N,N-dimethyl-formamide; toluene;
DOI:10.1021/jo00362a014

Reference yield:

: 286-20-4
cyclohexane-1,2-epoxide

: 101859-31-8
(1R*,2S*,(2E))-2-((tert-butyldimethylsilyl)oxy)cyclohexane-3-methyl-2-buten-4-ol

Guidance literature:: Multi-step reaction with 5 steps

1: 78 percent / tetrahydrofuran / 0 °C

2: 88 percent / TEA, DMAP / tetrahydrofuran; dimethylformamide

3: 86 percent / dibal / toluene / -78 - 0 °C

4: 90 percent / CHCl₃ / Heating

5: 94 percent / dibal / toluene / -78 - 0 °C

With dmap; TEA; diisobutylaluminium hydride; In tetrahydrofuran; chloroform; N,N-dimethyl-formamide; toluene;
DOI:10.1021/jo00362a014