D-Arginine, N2-L-phenylalanyl-

Base Information

Chemical Name:D-Arginine, N2-L-phenylalanyl-
CAS No.:39537-29-6
Molecular Formula:C₁₅H₂₃N₅O₃
Molecular Weight:321.379
Hs Code.:
DSSTox Substance ID:DTXSID80192659

Synonyms:D-Arginine, N2-L-phenylalanyl-;N2-L-Phenylalanyl-D-arginine;39537-29-6;C15-H23-N5-O3;DTXSID80192659

Suppliers and Price of D-Arginine, N2-L-phenylalanyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of D-Arginine, N2-L-phenylalanyl-

Chemical Property:

XLogP3:-3.7
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:9
Exact Mass:321.18008961
Heavy Atom Count:23
Complexity:417

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CC(C(=O)NC(CCCN=C(N)N)C(=O)O)N
Isomeric SMILES:C1=CC=C(C=C1)C[C@@H](C(=O)N[C@H](CCCN=C(N)N)C(=O)O)N

Technology Process of D-Arginine, N2-L-phenylalanyl-

There total 10 articles about D-Arginine, N2-L-phenylalanyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: (tert-butoxycarbonyl)-L-phenylalanyl-D-arginine

: 39537-29-6
H-Phe-D-Arg-OH

Guidance literature:: With trifluoroacetic acid; at 20 ℃; for 1h;
DOI:10.1007/BF02759162

Reference yield:

: 35661-40-6
N-Fmoc L-Phe

: 187618-60-6
N-α-[(9H-fluoren-9-ylmethoxy)carbonyl]-N^G-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-D-arginine

: 39537-29-6
H-Phe-D-Arg-OH

Guidance literature:: N-α-[(9H-fluoren-9-ylmethoxy)carbonyl]-N^G-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-D-arginine; With 1-methyl-1H-imidazole; diisopropyl-carbodiimide; at 20 ℃; for 2h; Green chemistry;

With piperidine; In N,N-dimethyl-formamide; for 0.133333h; Green chemistry;

N-Fmoc L-Phe; Further stages; Green chemistry;
DOI:10.1016/j.tetlet.2019.151058

Reference yield:

: 157-06-2,25212-18-4
D-arginine

: 39537-29-6
H-Phe-D-Arg-OH

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / dimethylformamide / 24 h / 20 °C

2: 87 percent / aq. TFA / 1 h / 20 °C

With trifluoroacetic acid; In N,N-dimethyl-formamide; 1: Condensation / 2: Hydrolysis;
DOI:10.1007/BF02759162