N-[[5-(acetamidomethyl)-2,4-dimethylphenyl]methyl]acetamide

Base Information

Chemical Name:N-[[5-(acetamidomethyl)-2,4-dimethylphenyl]methyl]acetamide
CAS No.:32280-53-8
Molecular Formula:C14H20 N2 O2
Molecular Weight:248.32
Hs Code.:2924299090
NSC Number:163172
DSSTox Substance ID:DTXSID00303881
Wikidata:Q82049372
Mol file:32280-53-8.mol

Synonyms:32280-53-8;n,n'-[(4,6-dimethyl-m-phenylene)dimethylene]bis-acetamide;N-[[5-(acetamidomethyl)-2,4-dimethylphenyl]methyl]acetamide;N,N'-(4,6-DIMETHYL-1,3-XYLYLENE)BISACETAMIDE;N,N'-((4,6-dimethyl-1,3-phenylene)bis(methylene))diacetamide;N,N'-[(4,6-Dimethyl-1,3-phenylene)bis(methylene)]diacetamide;NSC163172;DTXSID00303881;AKOS002364461;NSC-163172;FT-0747551;AG-205/04794008;F3308-2785;N-{5-[(acetylamino)methyl]-2,4-dimethylbenzyl}acetamide;N-[[5-(acetamido-methyl)-2,4-dimethyl-phenyl]-methyl]-acetamide

Suppliers and Price of N-[[5-(acetamidomethyl)-2,4-dimethylphenyl]methyl]acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N,N''-(4,6-Dimethyl-1,3-xylylene)bisacetamide
500mg
$ 110.00

TRC
N,N''-(4,6-Dimethyl-1,3-xylylene)bisacetamide
100mg
$ 60.00

Sigma-Aldrich
N,N'-(4,6-DIMETHYL-1,3-XYLYLENE)BISACETAMIDE Aldrich
1g
$ 57.00

American Custom Chemicals Corporation
N,N'-(4,6-DIMETHYL-1,3-XYLYLENE)BISACETAMIDE 95.00%
10G
$ 1892.43

American Custom Chemicals Corporation
N,N'-(4,6-DIMETHYL-1,3-XYLYLENE)BISACETAMIDE 95.00%
5G
$ 1233.49

American Custom Chemicals Corporation
N,N'-(4,6-DIMETHYL-1,3-XYLYLENE)BISACETAMIDE 95.00%
1G
$ 711.89

Total 8 raw suppliers

Chemical Property of N-[[5-(acetamidomethyl)-2,4-dimethylphenyl]methyl]acetamide

Chemical Property:

Boiling Point:544oC at 760 mmHg
Flash Point:218.1oC
PSA：58.20000
Density:1.068g/cm3
LogP:2.35740
XLogP3:0.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:248.152477885
Heavy Atom Count:18
Complexity:276

Purity/Quality:

99% ^*data from raw suppliers

N,N''-(4,6-Dimethyl-1,3-xylylene)bisacetamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C=C1CNC(=O)C)CNC(=O)C)C

Technology Process of N-[[5-(acetamidomethyl)-2,4-dimethylphenyl]methyl]acetamide

There total 2 articles about N-[[5-(acetamidomethyl)-2,4-dimethylphenyl]methyl]acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 108-38-3,104809-90-7
m-xylene

: 75-05-8,26809-02-9
acetonitrile

: 32280-53-8
N,N'-diacetyl-1,3-bis(aminomethyl)-4,6-dimethylbenzene

Guidance literature:: With sulfuric acid; Yield given. Multistep reaction; 1.) glacial acetic acid, from 60 to 65 deg C, 2.) glacial acetic acid, 90 deg C, 20 h;

Reference yield:

: 32280-53-8
N,N'-diacetyl-1,3-bis(aminomethyl)-4,6-dimethylbenzene

Guidance literature:: m-Xylol, Paraformaldehyd, Acetonitril, H3PO4, Δ;
DOI:10.1021/jo01081a016

Reference yield:

: 32280-53-8
N,N'-diacetyl-1,3-bis(aminomethyl)-4,6-dimethylbenzene

: 154621-52-0
N'-((tert-butyloxy)carbonyl)-1,3-bis(aminomethyl)-4,6-dimethylbenzene

Guidance literature:: Multi-step reaction with 2 steps

1: 3 N aq. HCl / 20 h / Heating

2: Et₃N / dimethylformamide / 0.17 h / 25 °C

With hydrogenchloride; triethylamine; In N,N-dimethyl-formamide;