N-(N'-tert-Butoxycarbonylleucyl-6-aminohexanoyl)benzoaza-15-crown-5

Base Information

Chemical Name:N-(N'-tert-Butoxycarbonylleucyl-6-aminohexanoyl)benzoaza-15-crown-5
CAS No.:145611-62-7
Molecular Formula:C31H51 N3 O8
Molecular Weight:593.761
Hs Code.:
DSSTox Substance ID:DTXSID40932654
Wikidata:Q76278783
Mol file:145611-62-7.mol

Synonyms:N-(N'-tert-Butoxycarbonylleucyl-6-aminohexanoyl)benzoaza-15-crown-5;145611-62-7;Carbamic acid, (3-methyl-1-(((6-(2,3,5,6,8,9,11,12-octahydro-7H-1,4,10,13,7-benzotetraoxaazacyclopentadecin-7-yl)-6-oxohexyl)amino)carbonyl)butyl)-, 1,1-dimethyl ester, (S)-;C31H51N3O8;C31-H51-N3-O8;DTXSID40932654;LS-50315;2-{[tert-Butoxy(hydroxy)methylidene]amino}-4-methyl-N-[6-(2,3,5,6,8,9,11,12-octahydro-7H-1,4,10,13,7-benzotetraoxazacyclopentadecin-7-yl)-6-oxohexyl]pentanimidic acid

Suppliers and Price of N-(N'-tert-Butoxycarbonylleucyl-6-aminohexanoyl)benzoaza-15-crown-5

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(N'-tert-Butoxycarbonylleucyl-6-aminohexanoyl)benzoaza-15-crown-5

Chemical Property:

Vapor Pressure:1.22E-23mmHg at 25°C
Boiling Point:770.2°Cat760mmHg
Flash Point:419.6°C
Density:1.081g/cm³
XLogP3:3.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:12
Exact Mass:593.36761559
Heavy Atom Count:42
Complexity:765

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)CC(C(=O)NCCCCCC(=O)N1CCOCCOC2=CC=CC=C2OCCOCC1)NC(=O)OC(C)(C)C
Isomeric SMILES:CC(C)C[C@@H](C(=O)NCCCCCC(=O)N1CCOCCOC2=CC=CC=C2OCCOCC1)NC(=O)OC(C)(C)C

Technology Process of N-(N'-tert-Butoxycarbonylleucyl-6-aminohexanoyl)benzoaza-15-crown-5

There total 4 articles about N-(N'-tert-Butoxycarbonylleucyl-6-aminohexanoyl)benzoaza-15-crown-5 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 3392-09-4
Boc-Leu-ONSu

: 6-Amino-1-(6,7,9,10,12,13,15,16-octahydro-5,8,14,17-tetraoxa-11-aza-benzocyclopentadecen-11-yl)-hexan-1-one; hydrochloride

: 145611-62-7
N-(N'-tert-butoxycarbonylleucyl-6-aminohexanoyl)benzoaza-15-crown-5

Guidance literature:: With triethylamine; In N,N-dimethyl-formamide; for 18h; Ambient temperature;
DOI:10.1007/BF00772913

Reference yield:

: 6404-29-1
6-(tert-butoxycarbonylamino)hexanoic acid

: 145611-62-7
N-(N'-tert-butoxycarbonylleucyl-6-aminohexanoyl)benzoaza-15-crown-5

Guidance literature:: Multi-step reaction with 3 steps

1: 91 percent / HBT, DCCl / CH₂Cl₂ / 19 h / 0 - 6 °C

2: HCl, anisole / dioxane

3: 94 percent / Et₃N / dimethylformamide / 18 h / Ambient temperature

With hydrogenchloride; benzotriazol-1-ol; methoxybenzene; triethylamine; dicyclohexyl-carbodiimide; In 1,4-dioxane; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1007/BF00772913

Reference yield:

: 145594-18-9
N-(N'-tert-butoxycarbonyl-6-aminohexanoyl)benzoaza-15-crown-5

: 145611-62-7
N-(N'-tert-butoxycarbonylleucyl-6-aminohexanoyl)benzoaza-15-crown-5

Guidance literature:: Multi-step reaction with 2 steps

1: HCl, anisole / dioxane

2: 94 percent / Et₃N / dimethylformamide / 18 h / Ambient temperature

With hydrogenchloride; methoxybenzene; triethylamine; In 1,4-dioxane; N,N-dimethyl-formamide;
DOI:10.1007/BF00772913