Dimethylarsinous acid

Base Information

• Chemical Name: Dimethylarsinous acid
• CAS No.: 55094-22-9
• Molecular Formula: C2H7 As O
• Molecular Weight: 121.999
• Hs Code.: 2931900090
• DSSTox Substance ID: DTXSID00203615
• Nikkaji Number: J622.643D
• Wikidata: Q27109814
• Mol file: 55094-22-9.mol

Synonyms:dimethylarsinite;dimethylarsinous acid

Chemical Property of Dimethylarsinous acid

Chemical Property:

• Vapor Pressure: 9.47mmHg at 25°C
• Boiling Point: 115.7°C at 760 mmHg
• Flash Point: 36.2°C
• PSA: 20.23000
• LogP: 0.22980
• Solubility.: Water
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 121.971284
• Heavy Atom Count: 4
• Complexity: 13.5

Purity/Quality:

99% ^*data from raw suppliers

DIMETHYLARSINOUSACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C[As](C)O
• Uses: DIMETHYLARSINOUSACID is a highly toxic metabolite of inorganic arsenic. DIMETHYLARSINOUSACID can induce malignant transformation of human cells. DIMETHYLARSINOUSACID has been shown to be a rat bladder carcinogen, but without effects on the mouse urothelium. Hydroxydimethylarsine is a highly toxic metabolite of inorganic arsenic. Hydroxydimethylarsine can induce malignant transformation of human cells. Hydroxydimethylarsine has been shown to be a rat bladder carcinogen, but without effects on the mouse urothelium.

Technology Process of Dimethylarsinous acid

There total 3 articles about Dimethylarsinous acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C2H7AsOS (754217-65-7) → dimethylarsinous acid (55094-22-9) + dimethyldithiolated arsinic acid (65165-11-9)

Guidance literature:

With GLUTATHIONE; In phosphate buffer; at 37 ℃; for 12h; pH=9;

DOI:10.1021/tx700346z

Reference yield:

dimethyliodoarsine (676-75-5) → dimethylarsinous acid (55094-22-9)

Guidance literature:

With water;

DOI:10.1021/ac034868u

Reference yield:

Dimethylarsinic acid (75-60-5) → dimethylarsinous acid (55094-22-9)

Guidance literature:

With sodium metabisulfite; Tris-HCl buffered saline; sodium thiosulfate; at 20 ℃; for 2h; pH=7.4;

DOI:10.1021/tx015537k

upstream raw materials:

Dimethylarsinic acid

dimethyliodoarsine

C₂H₇AsOS

Downstream raw materials:

Dimethylarsinic acid

Refernces

• 1、 Cheng, Jinduo,Ji, Wenjuan,Ma, Suze,Ji, Xinjian,Deng, Zixin,Ding, Wei,Zhang, Qi. "Characterization and Mechanistic Study of the Radical SAM Enzyme ArsS Involved in Arsenosugar Biosynthesis". supporting information. p. 7570 - 7575. Retrieved 2021/03/01.
• 2、 Lu, Xiufen,Arnold, Lora L.,Cohen, Samuel M.,Cullen, William R.,Le, X. Chris. "Speciation of Dimethylarsinous Acid and Trimethylarsine Oxide in Urine from Rats Fed with Dimethylarsinic Acid and Dimercaptopropane Sulfonate". . p. 6463 - 6468. Retrieved 2007/10/03.