N,N'-(9-Oxo-9H-fluorene-2,7-diyl)bis[1-pyrrolidineacetamide]

Base Information

• Chemical Name: N,N'-(9-Oxo-9H-fluorene-2,7-diyl)bis[1-pyrrolidineacetamide]
• CAS No.: 64953-57-7
• Molecular Formula: C₂₅H₂₈N₄O₃
• Molecular Weight: 432.522
• Hs Code.: 2933990090
• Mol file: 64953-57-7.mol

Synonyms:2,7-Bis((pyrrolidino)acetamido)fluoren-9-one;2,7-bis[2-(pyrrolidino)acetamido]-9-fluorenone;N,N'-(9-oxo-9H-fluorene-2,7-diyl)bis[2-(pyrrolidin-1-yl)acetamide];1-Pyrrolidineacetamide,N,N'-(9-oxo-9H-fluorene-2,7-diyl)bis;N,N'-(9-Oxo-9H-fluorene-2,7-diyl)bis-1-pyrrolidineacetamide;

Chemical Property of N,N'-(9-Oxo-9H-fluorene-2,7-diyl)bis[1-pyrrolidineacetamide]

Chemical Property:

• Boiling Point: 728.2°Cat760mmHg
• Flash Point: 394.2°C
• PSA: 88.73000
• Density: 1.34g/cm³
• LogP: 4.14140

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N,N'-(9-Oxo-9H-fluorene-2,7-diyl)bis[1-pyrrolidineacetamide]

There total 3 articles about N,N'-(9-Oxo-9H-fluorene-2,7-diyl)bis[1-pyrrolidineacetamide] which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

pyrrolidine (123-75-1) + 2,7-Bis(chloracetylamino)-9H-fluoren-9-one (59635-65-3) → 2,7-bis[2-(pyrrolidino)acetamido]-9-fluorenone (64953-57-7)

Guidance literature:

With dmap; In N,N-dimethyl-formamide; at 130 ℃; for 2h; Autoclave;

DOI:10.1016/j.bmc.2013.09.006

Reference yield:

2,7-dinitro-9-fluorenone (31551-45-8) → 2,7-bis[2-(pyrrolidino)acetamido]-9-fluorenone (64953-57-7)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium sulfide; sodium hydroxide / ethanol / 6 h / Reflux

2: N,N-dimethyl-formamide / 2 h / 20 °C

3: dmap / N,N-dimethyl-formamide / 2 h / 130 °C / Autoclave

With dmap; sodium sulfide; sodium hydroxide; In ethanol; N,N-dimethyl-formamide;

DOI:10.1016/j.bmc.2013.09.006

Reference yield:

2,7-diaminofluoren-9-one (2915-84-6) → 2,7-bis[2-(pyrrolidino)acetamido]-9-fluorenone (64953-57-7)

Guidance literature:

Multi-step reaction with 2 steps

1: N,N-dimethyl-formamide / 2 h / 20 °C

2: dmap / N,N-dimethyl-formamide / 2 h / 130 °C / Autoclave

With dmap; In N,N-dimethyl-formamide;

DOI:10.1016/j.bmc.2013.09.006

upstream raw materials:

2,7-dinitro-9-fluorenone

pyrrolidine

2,7-Bis(chloracetylamino)-9H-fluoren-9-one

2,7-diaminofluoren-9-one