2-Pyrimidinamine, N-(1-((3-methylphenyl)methyl)-4-piperidinyl)-

Base Information

Chemical Name:2-Pyrimidinamine, N-(1-((3-methylphenyl)methyl)-4-piperidinyl)-
CAS No.:76167-66-3
Molecular Formula:C₁₇H₂₂N₄
Molecular Weight:282.388
Hs Code.:
DSSTox Substance ID:DTXSID40227017
Wikidata:Q83106621
Mol file:76167-66-3.mol

Synonyms:76167-66-3;2-Pyrimidinamine, N-(1-((3-methylphenyl)methyl)-4-piperidinyl)-;Pyrimidine, 2-((1-(m-methylbenzyl)-4-piperidyl)amino)-;N-(1-((3-Methylphenyl)methyl)-4-piperidinyl)-2-pyrimidinamine;DTXSID40227017;LS-134498

Suppliers and Price of 2-Pyrimidinamine, N-(1-((3-methylphenyl)methyl)-4-piperidinyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 2-Pyrimidinamine, N-(1-((3-methylphenyl)methyl)-4-piperidinyl)-

Chemical Property:

Vapor Pressure:5.48E-08mmHg at 25°C
Boiling Point:441.3°C at 760 mmHg
Flash Point:220.7°C
PSA：41.05000
Density:1.159g/cm³
LogP:2.87240
XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:282.18444672
Heavy Atom Count:21
Complexity:295

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=CC=C1)CN2CCC(CC2)NC3=NC=CC=N3

Technology Process of 2-Pyrimidinamine, N-(1-((3-methylphenyl)methyl)-4-piperidinyl)-

There total 2 articles about 2-Pyrimidinamine, N-(1-((3-methylphenyl)methyl)-4-piperidinyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

: 1722-12-9,1195939-87-7
2-chloropyrimidine

: 82378-82-3
1-(m-methylbenzyl)-4-aminopiperidine

: 76167-66-3
[1-(3-Methyl-benzyl)-piperidin-4-yl]-pyrimidin-2-yl-amine

Guidance literature:: With potassium carbonate; In xylene; for 24h; Heating;

Reference yield:

: 1-(m-methylbenzyl)-4-piperidone oxime

: 76167-66-3
[1-(3-Methyl-benzyl)-piperidin-4-yl]-pyrimidin-2-yl-amine

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / LiAlH₄ / diethyl ether; tetrahydrofuran / 19 h / Heating

2: 46 percent / K₂CO₃ / xylene / 24 h / Heating

With lithium aluminium tetrahydride; potassium carbonate; In tetrahydrofuran; diethyl ether; xylene;