2,6-DI-Tert-butyl-4-methylphenyldiazo acetate

Base Information

Chemical Name:2,6-DI-Tert-butyl-4-methylphenyldiazo acetate
CAS No.:125640-92-8
Molecular Formula:C17H24 N2 O2
Molecular Weight:288.39
Hs Code.:
DSSTox Substance ID:DTXSID90925197
Nikkaji Number:J1.301.577E
Mol file:125640-92-8.mol

Synonyms:2,6-DI-TERT-BUTYL-4-METHYLPHENYLDIAZO ACETATE;125640-92-8;(2,6-ditert-butyl-4-methylphenyl) 2-diazoacetate;DTXSID90925197;AKOS025211857;FT-0610725;2,6-di-t-butyl-4-methyl-phenyl diazoacetate;2,6-di-tert-butyl-4-methylphenyl diazoacetate;2,6-di-tert-butyl-4-methylphenyl 2-diazoacetate;2,6-Di-tert.-butyl-4-methylphenyldiazo acetate;Diazoacetic acid 2,6-ditert-butyl-4-methylphenyl ester

Suppliers and Price of 2,6-DI-Tert-butyl-4-methylphenyldiazo acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2,6-DI-TERT-BUTYL-4-METHYLPHENYLDIAZO ACETATE 95.00%
5MG
$ 505.22

Total 5 raw suppliers

Chemical Property of 2,6-DI-Tert-butyl-4-methylphenyldiazo acetate

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
PSA：63.69000
Density:g/cm³
LogP:3.87706
XLogP3:5.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:288.183778013
Heavy Atom Count:21
Complexity:401

Purity/Quality:

98%Min ^*data from raw suppliers

2,6-DI-TERT-BUTYL-4-METHYLPHENYLDIAZO ACETATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C(=C1)C(C)(C)C)OC(=O)C=[N+]=[N-])C(C)(C)C

Technology Process of 2,6-DI-Tert-butyl-4-methylphenyldiazo acetate

There total 3 articles about 2,6-DI-Tert-butyl-4-methylphenyldiazo acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 2,6-di-tert-butyl-4-methylphenyl 3-oxobutanoate

: 125640-92-8
2,6-di-tert-butyl-4-methylphenyl diazoacetate

Guidance literature:: 2,6-di-tert-butyl-4-methylphenyl 3-oxobutanoate; With 4-toluenesulfonyl azide; triethylamine; In acetonitrile; at 20 ℃; for 20h; Inert atmosphere;

With potassium hydroxide; In water; acetonitrile; for 4h;
DOI:10.1021/acs.orglett.0c01150

Reference yield:

: 128-37-0
2,6-di-tert-butyl-4-methyl-phenol

: 125640-92-8
2,6-di-tert-butyl-4-methylphenyl diazoacetate

Guidance literature:: Multi-step reaction with 2 steps

1: 76 percent / triethylamine, methanesulfonyl azide / acetonitrile / 1.) reflux, 2.) RT, 7 h

2: 5percent aq. KOH / acetonitrile / 24 h / Ambient temperature

With potassium hydroxide; triethylamine; Methanesulfonyl azide; In acetonitrile;