L-Tyrosine, 2-(2-oxo-2-(10H-phenothiazin-10-yl)ethyl)hydrazide

Base Information

Chemical Name:L-Tyrosine, 2-(2-oxo-2-(10H-phenothiazin-10-yl)ethyl)hydrazide
CAS No.:84409-82-5
Molecular Formula:C₂₃H₂₂N₄O₃S
Molecular Weight:434.519
Hs Code.:
DSSTox Substance ID:DTXSID60233377
Wikidata:Q76156881

Synonyms:BRN 5661740;L-Tyrosine, 2-(2-oxo-2-(10H-phenothiazin-10-yl)ethyl)hydrazide;84409-82-5;DTXSID60233377;LS-158330

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Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of L-Tyrosine, 2-(2-oxo-2-(10H-phenothiazin-10-yl)ethyl)hydrazide

Chemical Property:

Boiling Point:713.8°Cat760mmHg
Flash Point:385.5°C
Density:1.377g/cm³
XLogP3:2.8
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:434.14126175
Heavy Atom Count:31
Complexity:606

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)N(C3=CC=CC=C3S2)C(=O)CNNC(=O)C(CC4=CC=C(C=C4)O)N
Isomeric SMILES:C1=CC=C2C(=C1)N(C3=CC=CC=C3S2)C(=O)CNNC(=O)[C@H](CC4=CC=C(C=C4)O)N

Technology Process of L-Tyrosine, 2-(2-oxo-2-(10H-phenothiazin-10-yl)ethyl)hydrazide

There total 2 articles about L-Tyrosine, 2-(2-oxo-2-(10H-phenothiazin-10-yl)ethyl)hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 786-50-5
10-chloroacetylphenothiazine

: 84409-82-5
2-Amino-3-(4-hydroxy-phenyl)-propionic acid N'-(2-oxo-2-phenothiazin-10-yl-ethyl)-hydrazide

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / N₂H₄*H₂O / ethanol / 18 h / Heating

2: 2.) NMe₃ / 1.) EtOH, room temp., 1 h, reflux, 3 h; 2.) 1 h

With hydrazine hydrate; trimethylamine; In ethanol;