N-(4-Chlorophenyl)-2-cyanoacetamide

Base Information

Chemical Name:N-(4-Chlorophenyl)-2-cyanoacetamide
CAS No.:17722-17-7
Molecular Formula:C9H7 Cl N2 O
Molecular Weight:194.62
Hs Code.:2926909090
European Community (EC) Number:241-720-7
UNII:5B6RP9K465
DSSTox Substance ID:DTXSID9066253
Nikkaji Number:J287.135A
Wikidata:Q81992840
Mol file:17722-17-7.mol

Synonyms:N-(4-Chlorophenyl)-2-cyanoacetamide;17722-17-7;4'-Chloro-2-cyanoacetanilide;Acetamide, N-(4-chlorophenyl)-2-cyano-;4-Chlorocyanoacetanilide;2-Cyano-N-(4-chlorophenyl)-acetamide;p-chlorocyanoacetanilide;5B6RP9K465;EINECS 241-720-7;MFCD00036015;Maybridge1_001531;UNII-5B6RP9K465;SCHEMBL1618221;DTXSID9066253;HMS545N13;n-(4-chlorophenyl)cyanoacetamide;4-Chloro-.alpha.-cyanoacetanilide;4-CHLORO-2-CYANOACETANILIDE;N-(4-Chlorophenyl)-2-cyanoacetamde;STK696462;4'-Chloro-2-cyanoacetanilide, 98%;AKOS000202516;N-(4-chlorophenyl)-2-cyano-acetamide;CYANOACETIC ACID P-CHLOROANILIDE;BB 0218826;CS-0268352;FT-0618011;9B-047;E78008;N-(4-CHLOROPHENYL)-.ALPHA.-CYANOACETAMIDE;J-011262;J-523047;Z56837087;F1673-4495

Suppliers and Price of N-(4-Chlorophenyl)-2-cyanoacetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
N-(4-Chlorophenyl)-2-cyanoacetamide >95%
500mg
$ 118.00

Matrix Scientific
N-(4-Chlorophenyl)-2-cyanoacetamide >95%
1g
$ 151.00

Matrix Scientific
N-(4-Chlorophenyl)-2-cyanoacetamide >95%
5g
$ 346.00

Biosynth Carbosynth
N-(4-Chlorophenyl)-2-cyanoacetamide
5 g
$ 436.00

Biosynth Carbosynth
N-(4-Chlorophenyl)-2-cyanoacetamide
10 g
$ 741.00

Biosynth Carbosynth
N-(4-Chlorophenyl)-2-cyanoacetamide
1 g
$ 128.00

Biosynth Carbosynth
N-(4-Chlorophenyl)-2-cyanoacetamide
2 g
$ 218.00

Biosynth Carbosynth
N-(4-Chlorophenyl)-2-cyanoacetamide
500 mg
$ 75.00

Azepine
N-(4-Chlorophenyl)-2-cyanoacetamide 95
1 g
$ 49.00

Azepine
N-(4-Chlorophenyl)-2-cyanoacetamide 95
5 g
$ 99.00

Total 18 raw suppliers

Chemical Property of N-(4-Chlorophenyl)-2-cyanoacetamide

Chemical Property:

Melting Point:207-209 °C(lit.)
Boiling Point:427.4oC at 760 mmHg
Flash Point:212.3oC
PSA：52.89000
Density:1.348g/cm3
LogP:2.26518
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:194.0246905
Heavy Atom Count:13
Complexity:225

Purity/Quality:

99% ^*data from raw suppliers

N-(4-Chlorophenyl)-2-cyanoacetamide >95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 20/21/22-36/37/38
Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=CC(=CC=C1NC(=O)CC#N)Cl

Technology Process of N-(4-Chlorophenyl)-2-cyanoacetamide

There total 7 articles about N-(4-Chlorophenyl)-2-cyanoacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 106-47-8
4-chloro-aniline

: 105-56-6
ethyl 2-cyanoacetate

: 17722-17-7
N-(4-chlorophenyl)-2-cyanoacetamide

Guidance literature:: In neat (no solvent); at 180 - 190 ℃;
DOI:10.1007/BF00515022

Reference yield: 89.0%

: 106-47-8
4-chloro-aniline

: 372-09-8
cyanoacetic acid

: 17722-17-7
N-(4-chlorophenyl)-2-cyanoacetamide

Guidance literature:: With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 1h; Inert atmosphere;
DOI:10.1021/acs.jmedchem.7b00020